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Circulating Tumor Cells: Detection Methods and Potential Clinical Application in Breast Cancer

Authors
 Seung Il Kim  ;  Hyo-il Jung 
Citation
 JOURNAL OF BREAST CANCER, Vol.13(2) : 125-131, 2010 
Journal Title
 JOURNAL OF BREAST CANCER 
ISSN
 1738-6756 
Issue Date
2010
Keywords
Breast neoplasms ; Circulating neoplastic cells ; Clinical application ; Detection
Abstract
Circulating tumor cells (CTCs) are defined as tumor cells circulating in the peripheral blood of patients. CTCs have long been regarded as an attractive research topic. Because of recent technological advances, it is now possible to detect CTCs in the bloodstream. Interestingly, CTCs are present in both of patients with metastatic disease and early stage localized disease in patients with breast cancer. An assay detecting CTCs seems to have significant future potential value in the clinical management of breast cancer as a prognostic marker, monitoring treatment response and selecting target therapy. This review addresses the technical overview of detection methods, possible clinical application and future direction of CTCs research
Files in This Item:
T201002160.pdf Download
DOI
10.4048/jbc.2010.13.2.125
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Il(김승일)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101436
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