Cited 14 times in
Relationship of body composition and C-reactive protein with pulmonary function
DC Field | Value | Language |
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dc.contributor.author | 심재용 | - |
dc.contributor.author | 이용제 | - |
dc.contributor.author | 이혜리 | - |
dc.contributor.author | 정동혁 | - |
dc.date.accessioned | 2015-04-23T16:51:16Z | - |
dc.date.available | 2015-04-23T16:51:16Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101353 | - |
dc.description.abstract | OBJECTIVES: It has been observed that restrictive pulmonary function is associated with obesity and C-reactive protein (CRP), an indicator for systemic inflammation. However, the interrelationship among body composition, CRP, and restrictive pulmonary function has been poorly understood. This study focused on the combined effects of body composition and CRP on restrictive pulmonary function. METHODS: We performed a cross-sectional study to examine the association of body composition and CRP with restrictive pulmonary function in 12,787 subjects (7083 men, 5704 women; ages 20-75 yr). We evaluated body composition and CRP as a categorical variable (non-obesity, percentage body fat <or=75 percentile; obesity, percentage body fat >75 percentile; low-inflammation, CRP <or=75 percentile; high-inflammation, CRP >75 percentile) and constructed 4 groups, which were non-overlapping (reference, inflammatory, obese, obese and inflammatory). The odds ratios (ORs) and 95% confidence intervals (CIs) for restrictive pulmonary function were calculated across all 4 groups. RESULTS: The adjusted ORs (95% CIs) for restrictive pulmonary function according to the 4 groups were 1.00(reference), 1.19(0.93-1.52), 2.01(1.53-2.64) and 3.51(2.60-4.74) in men and 1.00 (reference), 1.26 (0.96-1.69), 1.02 (0.58-1.81), and 3.32 (2.09-5.27) in women after adjusting for confounding variables. Interaction was found between the body fat percentage and CRP in women only (P < 0.05). CONCLUSIONS: In summary, the coexistence of high fat accumulation and systemic subclinical inflammation is associated with restrictive pulmonary function. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1197~1203 | - |
dc.relation.isPartOf | RESPIRATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adipose Tissue/metabolism* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Body Composition/physiology* | - |
dc.subject.MESH | C-Reactive Protein/metabolism* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Inflammation/metabolism | - |
dc.subject.MESH | Lung/physiopathology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Obesity/complications | - |
dc.subject.MESH | Obesity/metabolism* | - |
dc.subject.MESH | Obesity/physiopathology* | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Respiratory Function Tests/methods | - |
dc.subject.MESH | Young Adult | - |
dc.title | Relationship of body composition and C-reactive protein with pulmonary function | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학) | - |
dc.contributor.googleauthor | Dong-Hyuk Jung | - |
dc.contributor.googleauthor | Jae-Yong Shim | - |
dc.contributor.googleauthor | Hong-Yup Ahn | - |
dc.contributor.googleauthor | Hye-Ree Lee | - |
dc.contributor.googleauthor | Jung-Hyun Lee | - |
dc.contributor.googleauthor | Yong-Jae Lee | - |
dc.identifier.doi | 10.1016/j.rmed.2010.02.014 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02207 | - |
dc.contributor.localId | A02982 | - |
dc.contributor.localId | A03595 | - |
dc.contributor.localId | A03310 | - |
dc.relation.journalcode | J02615 | - |
dc.identifier.eissn | 1532-3064 | - |
dc.identifier.pmid | 20299196 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0954611110000843 | - |
dc.subject.keyword | Obesity | - |
dc.subject.keyword | Body composition | - |
dc.subject.keyword | Inflammation | - |
dc.subject.keyword | Pulmonary function | - |
dc.contributor.alternativeName | Shim, Jae Yong | - |
dc.contributor.alternativeName | Lee, Yong Jae | - |
dc.contributor.alternativeName | Lee, Hye Ree | - |
dc.contributor.alternativeName | Jung, Dong Hyuk | - |
dc.contributor.affiliatedAuthor | Shim, Jae Yong | - |
dc.contributor.affiliatedAuthor | Lee, Yong Jae | - |
dc.contributor.affiliatedAuthor | Jung, Dong Hyuk | - |
dc.contributor.affiliatedAuthor | Lee, Hye Ree | - |
dc.citation.volume | 104 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1197 | - |
dc.citation.endPage | 1203 | - |
dc.identifier.bibliographicCitation | RESPIRATORY MEDICINE, Vol.104(8) : 1197-1203, 2010 | - |
dc.identifier.rimsid | 51004 | - |
dc.type.rims | ART | - |
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