Cited 26 times in
New cfiA variant and novel insertion sequence elements in carbapenem-resistant Bacteroides fragilis isolates from Korea.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김신영 | - |
dc.contributor.author | 김준명 | - |
dc.contributor.author | 용동은 | - |
dc.contributor.author | 이경원 | - |
dc.contributor.author | 정석훈 | - |
dc.contributor.author | 정윤섭 | - |
dc.date.accessioned | 2015-04-23T16:46:12Z | - |
dc.date.available | 2015-04-23T16:46:12Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101191 | - |
dc.description.abstract | Of 276 nonduplicate Bacteroides fragilis clinical isolates recovered from 1997 to 2004, 3 were resistant to carbapenem. cepA and cfiA alleles were detected by polymerase chain reaction in 240 (87.0%) and 11 (4.0%) of the isolates, respectively. Insertion sequence (IS) elements were found only in the 3 carbapenem-resistant B. fragilis isolates, which produced metallo-beta-lactamase at a level detectable by UV spectrophotometry. Sequence analysis showed 1 new cfiA variant, cfiA(11), and 2 novel IS elements. The cfiA(11) gene revealed 5 amino acid substitutions compared to cfiA, with 97.6% amino acid identity. The transposase, terminal inverted repeat sequence, and target site duplication sequence of the 2 novel IS elements were unique. This study reconfirmed the correlation between ISs and carbapenem resistance in B. fragilis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 343~348 | - |
dc.relation.isPartOf | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Amino Acid Sequence | - |
dc.subject.MESH | Amino Acid Substitution/genetics | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology* | - |
dc.subject.MESH | Bacterial Proteins/biosynthesis | - |
dc.subject.MESH | Bacterial Proteins/genetics* | - |
dc.subject.MESH | Bacteroides Infections/microbiology | - |
dc.subject.MESH | Bacteroides fragilis/drug effects* | - |
dc.subject.MESH | Bacteroides fragilis/genetics* | - |
dc.subject.MESH | Bacteroides fragilis/isolation & purification | - |
dc.subject.MESH | Carbapenems/pharmacology* | - |
dc.subject.MESH | DNA Transposable Elements* | - |
dc.subject.MESH | DNA, Bacterial/chemistry | - |
dc.subject.MESH | DNA, Bacterial/genetics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Molecular Sequence Data | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Sequence Alignment | - |
dc.subject.MESH | Sequence Analysis, DNA | - |
dc.subject.MESH | Sequence Homology, Amino Acid | - |
dc.subject.MESH | beta-Lactam Resistance* | - |
dc.subject.MESH | beta-Lactamases/biosynthesis | - |
dc.subject.MESH | beta-Lactamases/genetics* | - |
dc.title | New cfiA variant and novel insertion sequence elements in carbapenem-resistant Bacteroides fragilis isolates from Korea. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Kyoung Ho Roh | - |
dc.contributor.googleauthor | Sinyoung Kim | - |
dc.contributor.googleauthor | Chang-Ki Kim | - |
dc.contributor.googleauthor | Jong Hwa Yum | - |
dc.contributor.googleauthor | Myung Sook Kim | - |
dc.contributor.googleauthor | Dongeun Yong | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.contributor.googleauthor | Yunsop Chong | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2009.11.003 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00675 | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A02423 | - |
dc.contributor.localId | A02649 | - |
dc.contributor.localId | A03619 | - |
dc.contributor.localId | A03679 | - |
dc.relation.journalcode | J00731 | - |
dc.identifier.eissn | 1879-0070 | - |
dc.identifier.pmid | 20226324 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0732889309004490 | - |
dc.contributor.alternativeName | Kim, Sin Young | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Yong, Dong Eun | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.alternativeName | Jeong, Seok Hoon | - |
dc.contributor.alternativeName | Chong, Yun Sop | - |
dc.contributor.affiliatedAuthor | Kim, Sin Young | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Yong, Dong Eun | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Jeong, Seok Hoon | - |
dc.contributor.affiliatedAuthor | Chong, Yun Sop | - |
dc.citation.volume | 66 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 343 | - |
dc.citation.endPage | 348 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.66(4) : 343-348, 2010 | - |
dc.identifier.rimsid | 52123 | - |
dc.type.rims | ART | - |
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