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Intravitreal bevacizumab in the management of subretinal fluid associated with choroidal osteoma

DC FieldValueLanguage
dc.contributor.author노미인-
dc.contributor.author이성철-
dc.date.accessioned2015-04-23T16:45:45Z-
dc.date.available2015-04-23T16:45:45Z-
dc.date.issued2010-
dc.identifier.issn0275-004X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101177-
dc.description.abstractPURPOSE: The purpose of this study was to evaluate the effect of intravitreal injection of bevacizumab on subretinal fluid associated with choroidal osteoma. METHODS: In this retrospective noncomparative case series, eyes with serous retinal detachment involving the macula were treated with intravitreal injection of bevacizumab (1.25 mg/0.05 mL) and carefully followed-up with complete ophthalmic examination, including angiography and optical coherence tomography. The changes in best-corrected visual acuity and central foveal thickness were assessed by optical coherence tomography. RESULTS: Six eyes received intravitreal injection of bevacizumab for serous retinal detachment. Only one eye had choroidal neovascularization associated with serous retinal detachment. The mean number of injections for the 6 eyes was 2.0 during the mean follow-up period of 11.3 months. The median logarithm of the minimum angle of resolution best-corrected visual acuity improved from 0.70 (Snellen equivalent, 20/100) at baseline to 0.30 (Snellen equivalent, 20/40; P = 0.043) at the final visit. The optical coherence tomography result also showed a significant reduction in central foveal thickness with a median central foveal thickness of 357.0 microm at baseline and 169.50 microm at the final visit (P = 0.028). The treatment was well tolerated, without ocular or systemic adverse events. CONCLUSION: Intravitreal injection of bevacizumab for serous retinal detachment secondary to choroidal osteoma resulted in both visual and anatomical improvements.-
dc.description.statementOfResponsibilityopen-
dc.format.extent945~951-
dc.relation.isPartOfRETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAngiogenesis Inhibitors/administration & dosage*-
dc.subject.MESHAntibodies, Monoclonal/administration & dosage*-
dc.subject.MESHAntibodies, Monoclonal, Humanized-
dc.subject.MESHBevacizumab-
dc.subject.MESHBody Fluids/drug effects-
dc.subject.MESHBone Neoplasms/complications*-
dc.subject.MESHBone Neoplasms/pathology-
dc.subject.MESHChoroid Neoplasms/complications*-
dc.subject.MESHChoroid Neoplasms/pathology-
dc.subject.MESHExudates and Transudates/drug effects-
dc.subject.MESHFemale-
dc.subject.MESHFluorescein Angiography-
dc.subject.MESHHumans-
dc.subject.MESHInjections-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOsteoma/complications*-
dc.subject.MESHOsteoma/pathology-
dc.subject.MESHRetinal Detachment/drug therapy*-
dc.subject.MESHRetinal Detachment/etiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTomography, Optical Coherence-
dc.subject.MESHVascular Endothelial Growth Factor A/antagonists & inhibitors-
dc.subject.MESHVisual Acuity/physiology-
dc.subject.MESHVitreous Body-
dc.titleIntravitreal bevacizumab in the management of subretinal fluid associated with choroidal osteoma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorSong, Ji Hun-
dc.contributor.googleauthorBae, Jeong Hun-
dc.contributor.googleauthorRho, Mi In-
dc.contributor.googleauthorLee, Sung Chul-
dc.identifier.doi10.1097/IAE.0b013e3181c720ca-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01279-
dc.contributor.localIdA02873-
dc.relation.journalcodeJ02621-
dc.identifier.eissn1539-2864-
dc.identifier.pmid20531145-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00006982-201006000-00015&LSLINK=80&D=ovft-
dc.contributor.alternativeNameRoh, Mi In-
dc.contributor.alternativeNameLee, Sung Chul-
dc.contributor.affiliatedAuthorRoh, Mi In-
dc.contributor.affiliatedAuthorLee, Sung Chul-
dc.citation.volume30-
dc.citation.number6-
dc.citation.startPage945-
dc.citation.endPage951-
dc.identifier.bibliographicCitationRETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Vol.30(6) : 945-951, 2010-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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