Cited 9 times in
Comparison of genotypic resistance mutations in treatment-naive HIV type 1-infected patients in Korea and China
DC Field | Value | Language |
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dc.contributor.author | 김준명 | - |
dc.contributor.author | 백지현 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 용동은 | - |
dc.contributor.author | 임영선 | - |
dc.contributor.author | 진범식 | - |
dc.contributor.author | 진성준 | - |
dc.contributor.author | 채윤태 | - |
dc.contributor.author | 최준용 | - |
dc.contributor.author | 최희경 | - |
dc.contributor.author | 한상훈 | - |
dc.date.accessioned | 2015-04-23T16:45:08Z | - |
dc.date.available | 2015-04-23T16:45:08Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0889-2229 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101158 | - |
dc.description.abstract | Seventy-six treatment-naive human immunodeficiency virus (HIV)-1-infected patients were recruited from Korea and China to evaluate transmitted drug resistance (TDR). Although no major TDR was observed within the study population, some resistance-associated mutations in the reverse transcriptase region were observed (V118I 9.2%, V179D 7.9%). The frequencies of resistance-associated mutations in NNRTI (V179D) and PI minor mutations were higher in Korean patients compared with Chinese patients (13.6% vs. 0%, 45.5% vs. 12.5%, p < 0.05). Although unique clustering was observed in phylogenetic analyses according to geographic sources, cautious monitoring is recommended due to increasing TDR reports in this area where the population shares close geographic and cultural aspects. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 217~221 | - |
dc.relation.isPartOf | AIDS RESEARCH AND HUMAN RETROVIRUSES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | China | - |
dc.subject.MESH | Cluster Analysis | - |
dc.subject.MESH | Drug Resistance, Viral* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Geography | - |
dc.subject.MESH | HIV Infections/virology* | - |
dc.subject.MESH | HIV-1/drug effects* | - |
dc.subject.MESH | HIV-1/genetics* | - |
dc.subject.MESH | HIV-1/isolation & purification | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Molecular Epidemiology | - |
dc.subject.MESH | Molecular Sequence Data | - |
dc.subject.MESH | Mutation, Missense* | - |
dc.subject.MESH | Phylogeny | - |
dc.subject.MESH | Polymorphism, Genetic | - |
dc.subject.MESH | Sequence Analysis, DNA | - |
dc.subject.MESH | Viral Proteins/genetics* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Comparison of genotypic resistance mutations in treatment-naive HIV type 1-infected patients in Korea and China | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Yonsei Biomedical Research Center (연세의생명연구원) | - |
dc.contributor.googleauthor | Bum Sik Chin | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Yang Han | - |
dc.contributor.googleauthor | Jiqiu Kuang | - |
dc.contributor.googleauthor | Yanling Li | - |
dc.contributor.googleauthor | Sang Hoon Han | - |
dc.contributor.googleauthor | Heekyoung Choi | - |
dc.contributor.googleauthor | Yun Tae Chae | - |
dc.contributor.googleauthor | Sung Joon Jin | - |
dc.contributor.googleauthor | Ji-Hyeon Baek | - |
dc.contributor.googleauthor | Young-Soun Lim | - |
dc.contributor.googleauthor | Chang Oh Kim | - |
dc.contributor.googleauthor | Young Goo Song | - |
dc.contributor.googleauthor | Dongeun Yong | - |
dc.contributor.googleauthor | TaiSheng Li | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.identifier.doi | 10.1089/aid.2009.0157 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A01839 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A02423 | - |
dc.contributor.localId | A03384 | - |
dc.contributor.localId | A03981 | - |
dc.contributor.localId | A03983 | - |
dc.contributor.localId | A04022 | - |
dc.contributor.localId | A04191 | - |
dc.contributor.localId | A04228 | - |
dc.contributor.localId | A04286 | - |
dc.relation.journalcode | J00055 | - |
dc.identifier.eissn | 1931-8405 | - |
dc.identifier.pmid | 20156103 | - |
dc.identifier.url | http://online.liebertpub.com/doi/abs/10.1089/aid.2009.0157 | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Baek, Ji Hyeon | - |
dc.contributor.alternativeName | Song, Young Goo | - |
dc.contributor.alternativeName | Yong, Dong Eun | - |
dc.contributor.alternativeName | Im, Young Sun | - |
dc.contributor.alternativeName | Chin, Bum Sik | - |
dc.contributor.alternativeName | Jin, Sung Joon | - |
dc.contributor.alternativeName | Chae, Yun Tae | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.alternativeName | Choi, Hee Kyoung | - |
dc.contributor.alternativeName | Han, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Baek, Ji Hyeon | - |
dc.contributor.affiliatedAuthor | Song, Young Goo | - |
dc.contributor.affiliatedAuthor | Yong, Dong Eun | - |
dc.contributor.affiliatedAuthor | Im, Young Sun | - |
dc.contributor.affiliatedAuthor | Chin, Bum Sik | - |
dc.contributor.affiliatedAuthor | Jin, Sung Joon | - |
dc.contributor.affiliatedAuthor | Chae, Yun Tae | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Choi, Hee Kyoung | - |
dc.contributor.affiliatedAuthor | Han, Sang Hoon | - |
dc.citation.volume | 26 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 217 | - |
dc.citation.endPage | 221 | - |
dc.identifier.bibliographicCitation | AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol.26(2) : 217-221, 2010 | - |
dc.identifier.rimsid | 52106 | - |
dc.type.rims | ART | - |
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