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Predictive capability of anorectal physiologic tests for unfavorable outcomes following biofeedback therapy in dyssynergic defecation

 Jae Kook Shin  ;  Jae Hee Cheon  ;  Eun Sook Kim  ;  Jin Young Yoon  ;  Jin Ha Lee  ;  Soung Min Jeon  ;  Hyun Jung Bok  ;  Jae Jun Park  ;  Chang Mo Moon  ;  Sung Pil Hong  ;  Yong Chan Lee  ;  Won Ho Kim 
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.25(7) : 1060-1065, 2010 
Journal Title
Issue Date
Adult ; Aged ; Anal Canal/physiopathology* ; Ataxia/physiopathology* ; Ataxia/therapy ; Biofeedback, Psychology* ; Constipation*/physiopathology ; Constipation*/therapy ; Defecation/physiology* ; Defecography/methods ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Predictive Value of Tests ; Rectum/physiopathology* ; Treatment Outcome
Anorectal Manometry ; Balloon Expulsion Test ; Biofeedback, Psychology ; Defecogram ; Dyssynergic Defecation ; Predicting Factors
The purpose of this study is to evaluate the predictive capability of anorectal physiologic tests for unfavorable outcomes prior to the initiation of biofeedback therapy in patients with dyssynergic defecation. We analyzed a total of 80 consecutive patients who received biofeedback therapy for chronic idiopathic functional constipation with dyssynergic defecation. After classifying the patients into two groups (responders and non-responders), univariate and multivariate analyses were performed to determine the predictors associated with the responsiveness to biofeedback therapy. Of the 80 patients, 63 (78.7%) responded to biofeedback therapy and 17 (21.3%) did not. On univariate analysis, the inability to evacuate an intrarectal balloon (P=0.028), higher rectal volume for first, urgent, and maximal sensation (P=0.023, P=0.008, P=0.007, respectively), and increased anorectal angle during squeeze (P=0.020) were associated with poor outcomes. On multivariate analysis, the inability to evacuate an intrarectal balloon (P=0.018) and increased anorectal angle during squeeze (P=0.029) were both found to be independently associated with a lack of response to biofeedback therapy. Our data show that the two anorectal physiologic test factors are associated with poor response to biofeedback therapy for patients with dyssynergic defecation. These findings may assist physicians in predicting the responsiveness to therapy for this patient population
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
Kim, Eun Soo(김은수)
Moon, Chang Mo(문창모)
Park, Jae Jun(박재준)
Shin, Jae Kook(신재국)
Lee, Yong Chan(이용찬) ORCID logo https://orcid.org/0000-0001-8800-6906
Jeon, Soung Min(전승민)
Chung, Jae Bock(정재복)
Cheon, Jae Hee(천재희) ORCID logo https://orcid.org/0000-0002-2282-8904
Hong, Sung Pil(홍성필)
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