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Negative capsule endoscopy without subsequent enteroscopy does not predict lower long-term rebleeding rates in patients with obscure GI bleeding.

DC FieldValueLanguage
dc.contributor.author천재희-
dc.contributor.author홍성필-
dc.contributor.author김원호-
dc.contributor.author김태일-
dc.contributor.author김희만-
dc.contributor.author문창모-
dc.contributor.author박재준-
dc.contributor.author박현성-
dc.contributor.author이진하-
dc.date.accessioned2015-04-23T16:43:46Z-
dc.date.available2015-04-23T16:43:46Z-
dc.date.issued2010-
dc.identifier.issn0016-5107-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101115-
dc.description.abstractBACKGROUND: Capsule endoscopy (CE) is now widely accepted as a first-line diagnostic modality for obscure GI bleeding (OGIB). However, the clinical implications of negative results of CE studies remain unclear. OBJECTIVE: To investigate long-term (>1 year) outcomes for patients undergoing CE for OGIB and to identify risk factors associated with rebleeding. DESIGN AND SETTING: Retrospective study in a tertiary care hospital. METHODS: A total of 57 consecutive patients who had undergone CE for OGIB were enrolled and their pre- and post-CE clinical data were collected. Specific treatments were defined as treatments directly aimed at presumed bleeding causes including hemostasis and disease-specific medical therapy, whereas nonspecific treatments were defined as symptomatic treatments for anemia. RESULTS: Of the 57 patients, the indication for CE was obscure-overt bleeding in 46 patients and obscure-occult bleeding in 11 patients. Among 51 patients for whom long-term data were available, significant (P2) lesions were found in 23 (45.1%) patients. The overall rebleeding rate was 35.3% during a median follow-up duration of 31.7 months (range 12.8-58.0 months). There was no statistically significant difference in the cumulative rebleeding rate between patients with positive and negative CE results (34.8% vs 35.7%, respectively; P = .989). However, specific treatments after CE (hazard ratio, 0.111; 95% CI, 0.013-0.980; P = .043) significantly decreased rebleeding. LIMITATIONS: Small number of patients, retrospective study design. CONCLUSIONS: The rebleeding rate for patients with OGIB and negative CE results was substantial, indicating that these patients should be closely observed. However, specific treatment after CE significantly reduced the incidence of recurrent bleeding.-
dc.description.statementOfResponsibilityopen-
dc.format.extent990~997-
dc.relation.isPartOfGastrointestinal Endoscopy-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCapsule Endoscopy*-
dc.subject.MESHEndoscopy, Gastrointestinal-
dc.subject.MESHFemale-
dc.subject.MESHGastrointestinal Hemorrhage/etiology*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHRecurrence-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHTime Factors-
dc.titleNegative capsule endoscopy without subsequent enteroscopy does not predict lower long-term rebleeding rates in patients with obscure GI bleeding.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJae Jun Park-
dc.contributor.googleauthorJae Hee Cheon-
dc.contributor.googleauthorHee Man Kim-
dc.contributor.googleauthorHyeun Sung Park-
dc.contributor.googleauthorChang Mo Moon-
dc.contributor.googleauthorJin Ha Lee-
dc.contributor.googleauthorSung Pil Hong-
dc.contributor.googleauthorTae Il Kim-
dc.contributor.googleauthorWon Ho Kim-
dc.identifier.doi10.1016/j.gie.2009.12.009-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04404-
dc.contributor.localIdA00774-
dc.contributor.localIdA01079-
dc.contributor.localIdA01210-
dc.contributor.localIdA01390-
dc.contributor.localIdA01636-
dc.contributor.localIdA01740-
dc.contributor.localIdA03231-
dc.contributor.localIdA04030-
dc.relation.journalcodeJ00920-
dc.identifier.pmid20304392-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0016510709028636-
dc.contributor.alternativeNameCheon, Jae Hee-
dc.contributor.alternativeNameHong, Sung Pil-
dc.contributor.alternativeNameKim, Won Ho-
dc.contributor.alternativeNameKim, Tae Il-
dc.contributor.alternativeNameKim, Hee Man-
dc.contributor.alternativeNameMoon, Chang Mo-
dc.contributor.alternativeNamePark, Jae Jun-
dc.contributor.alternativeNamePark, Hyeun Sung-
dc.contributor.alternativeNameLee, Jin Ha-
dc.contributor.affiliatedAuthorHong, Sung Pil-
dc.contributor.affiliatedAuthorKim, Won Ho-
dc.contributor.affiliatedAuthorKim, Tae Il-
dc.contributor.affiliatedAuthorKim, Hee Man-
dc.contributor.affiliatedAuthorMoon, Chang Mo-
dc.contributor.affiliatedAuthorPark, Jae Jun-
dc.contributor.affiliatedAuthorPark, Hyeun Sung-
dc.contributor.affiliatedAuthorLee, Jin Ha-
dc.contributor.affiliatedAuthorCheon, Jae Hee-
dc.citation.volume71-
dc.citation.number6-
dc.citation.startPage990-
dc.citation.endPage997-
dc.identifier.bibliographicCitationGastrointestinal Endoscopy, Vol.71(6) : 990-997, 2010-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers

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