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Prognosis for craniofacial fibrous dysplasia after incomplete resection: age and serum alkaline phosphatase

DC Field Value Language
dc.contributor.author이원재-
dc.contributor.author김용욱-
dc.date.accessioned2015-04-23T16:34:48Z-
dc.date.available2015-04-23T16:34:48Z-
dc.date.issued2010-
dc.identifier.issn0901-5027-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100841-
dc.description.abstractComplete resection is usually impossible for fibrous dysplasia (FD) involving the cranial base. Incomplete resection could be followed by regrowth of FD, but there is no method for indicating disease progress. Serum alkaline phosphatase (ALP) is significantly high in patients with FD. The authors investigate the relationship between ALP, progress of FD, and age at surgery. 18 patients with craniofacial FD were separated into 3 groups: Group A, complete resection; Group B, incomplete resection followed by regrowth of FD; and Group C, incomplete resection but no regrowth of FD. Medical records and CT scans were reviewed retrospectively. ALP levels were obtained preoperatively, postoperatively and every year during follow-up. The relation between ALP and regrowth and that between age at surgery and regrowth were investigated. There was no recurrence in Group A (n=4). Regrowth in Group B (n=7) was preceded by an abrupt increase in ALP. In Group C (n=7), no regrowth was observed and ALP was maintained within the normal range. 6 patients (85%) in Group B and 2 (28%) in Group C were under 17 years old. The results revealed that the level of postoperative serum ALP could be a reliable marker for predicting the progress of craniofacial FD.-
dc.description.statementOfResponsibilityopen-
dc.format.extent221~226-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHAlkaline Phosphatase/blood*-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHBone Transplantation-
dc.subject.MESHChild-
dc.subject.MESHDisease Progression-
dc.subject.MESHFacial Bones/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHFibrous Dysplasia, Monostotic/blood-
dc.subject.MESHFibrous Dysplasia, Monostotic/surgery-
dc.subject.MESHFibrous Dysplasia, Polyostotic/blood-
dc.subject.MESHFibrous Dysplasia, Polyostotic/surgery*-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHForecasting-
dc.subject.MESHHumans-
dc.subject.MESHLongitudinal Studies-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOsteotomy/methods-
dc.subject.MESHPrognosis-
dc.subject.MESHRecurrence-
dc.subject.MESHRemission Induction-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSkull Base/surgery*-
dc.subject.MESHTomography, X-Ray Computed-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHYoung Adult-
dc.titlePrognosis for craniofacial fibrous dysplasia after incomplete resection: age and serum alkaline phosphatase-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Plastic Surgery & Reconstructive Surgery (성형외과학)-
dc.contributor.googleauthorB.Y. Park-
dc.contributor.googleauthorY.W. Cheon-
dc.contributor.googleauthorY.O. Kim-
dc.contributor.googleauthorN.S. Pae-
dc.contributor.googleauthorW.J. Lee-
dc.identifier.doi10.1016/j.ijom.2009.12.008-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03005-
dc.contributor.localIdA00749-
dc.relation.journalcodeJ01143-
dc.identifier.eissn1399-0020-
dc.identifier.pmid20083386-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0901502709011977-
dc.subject.keywordcraniofacial fibrous dysplasia-
dc.subject.keywordincomplete resection-
dc.subject.keywordage-
dc.subject.keywordalkaline phosphatase-
dc.subject.keywordprognostic factor-
dc.contributor.alternativeNameLee, Won Jai-
dc.contributor.alternativeNameKim, Yong Oock-
dc.contributor.affiliatedAuthorLee, Won Jai-
dc.contributor.affiliatedAuthorKim, Yong Oock-
dc.citation.volume39-
dc.citation.number3-
dc.citation.startPage221-
dc.citation.endPage226-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, Vol.39(3) : 221-226, 2010-
dc.identifier.rimsid55255-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers

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