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Spread of ropivacaine by a weight-based formula in a pediatric caudal block: a fluoroscopic examination

Authors
 B.-N. KOO  ;  J.-Y. HONG  ;  H. K. KIL 
Citation
 ACTA ANAESTHESIOLOGICA SCANDINAVICA, Vol.54(5) : 562-565, 2010 
Journal Title
ACTA ANAESTHESIOLOGICA SCANDINAVICA
ISSN
 0001-5172 
Issue Date
2010
MeSH
Amides/administration & dosage ; Amides/pharmacokinetics* ; Anesthesia, Caudal/methods* ; Anesthetics, Local/administration & dosage ; Anesthetics, Local/pharmacokinetics* ; Body Weight ; Child, Preschool ; Contrast Media/administration & dosage ; Contrast Media/pharmacokinetics ; Dose-Response Relationship, Drug ; Drug Compounding ; Fluoroscopy ; Hernia, Inguinal/surgery ; Humans ; Infant ; Lumbosacral Region/diagnostic imaging ; Male ; Nerve Block/methods ; Orchiopexy ; Spinal Cord/diagnostic imaging* ; Spinal Cord/metabolism
Abstract
BACKGROUND: Caudal block is the most common regional technique to provide post-operative analgesia in pediatric infra-umbilical surgery. This study was designed to define how many spinal segments would be covered by the weight-based dosage of caudally administered 0.2% ropivacaine in children using the fluoroscopic method.

METHODS: After an approval from the institutional human research review board, in 83 ASA I boys undergoing day-case urological surgery, the distribution of ropivacaine mixed with a radioactive dye in relation to the volume injected caudally was studied. Three groups were studied: for perineal surgery 0.5 ml/kg (group C(0.5)), for inguinal hernia repair 1 ml/kg (group C(1.0)), and for orchiopexy 1.25 ml/kg (group C(1.25)). The dose of 0.2% ropivacaine containing radiopaque dye at a ratio of 1 : 4 was injected at a rate of 1 ml 3 s(-1). Fluoroscopic examination was performed immediately to define the level of the drug spread within the extradural space.

RESULTS: The highest spinal levels [median with ranges] of spread were L2 [L4-T12] in group C(0.5), T12 [L1-T8] in group C(1.0), and T10 [L2-T7] in group C(1.25). Analysis by age distribution (infants: <12 months; toddlers: 12-36 months; and children: >36 months) revealed a larger spread in younger patients.

CONCLUSIONS: Based on the fluoroscopic findings, the weight-based doses for caudally administered 0.2% bupivacaine suggested by Armitage are also useful for ropivacaine to block the spinal level required for the different types of surgeries studied
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.2010.02224.x/abstract
DOI
10.1111/j.1399-6576.2010.02224.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Koo, Bon-Nyeo(구본녀) ORCID logo https://orcid.org/0000-0002-3189-1673
Kil, Hae Keum(길혜금)
Hong, Jeong Yeon(홍정연)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100836
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