1 239

Cited 38 times in

Do patients with ulcerative colitis diagnosed at a young age have more severe disease activity than patients diagnosed when older?

DC FieldValueLanguage
dc.contributor.author김원호-
dc.contributor.author김태일-
dc.contributor.author문창모-
dc.contributor.author박재준-
dc.contributor.author이진하-
dc.contributor.author천재희-
dc.contributor.author홍성필-
dc.date.accessioned2015-04-23T16:32:54Z-
dc.date.available2015-04-23T16:32:54Z-
dc.date.issued2010-
dc.identifier.issn0012-2823-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100784-
dc.description.abstractBACKGROUND/AIMS: To compare the clinical features and disease behavior of ulcerative colitis (UC) according to the age at onset. METHODS: This retrospective study included 455 patients with UC who were diagnosed and treated between 1990 and 2008 at a single tertiary institution in Korea. The patients were divided into 2 groups according to their age at diagnosis of UC: an elderly group (>or=40 years) and a young group (<40 years). Clinical findings at diagnosis, extent of disease, treatment modalities used, cumulative admission rates, cumulative relapse rates, and surgery rates were analyzed according to these age groups. RESULTS: Two hundred and forty-two patients with UC (53.2%) were diagnosed before the age of 40 years. Disease severity at initial presentation as assessed by diarrhea frequency, the presence of pancolitis, and the use of steroids were higher in the young group; however, clinical disease course including cumulative admission rates, cumulative relapse rates, and surgery rates were not significantly different between the 2 groups. CONCLUSIONS: Certain clinical features and the extent of disease in UC patients appear to be more severe when the disease is diagnosed at younger age; however, their disease course and prognosis might not be different from those of their older counterparts.-
dc.description.statementOfResponsibilityopen-
dc.format.extent237~243-
dc.relation.isPartOfDIGESTION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdrenal Cortex Hormones/administration & dosage-
dc.subject.MESHAdult-
dc.subject.MESHAge Distribution-
dc.subject.MESHAge Factors-
dc.subject.MESHBiopsy, Needle-
dc.subject.MESHCohort Studies-
dc.subject.MESHColitis, Ulcerative/diagnosis*-
dc.subject.MESHColitis, Ulcerative/drug therapy-
dc.subject.MESHColitis, Ulcerative/epidemiology*-
dc.subject.MESHDisease Progression-
dc.subject.MESHEarly Diagnosis-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImmunohistochemistry-
dc.subject.MESHImmunosuppressive Agents/administration & dosage-
dc.subject.MESHIncidence-
dc.subject.MESHIntestinal Mucosa/pathology-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrognosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHYoung Adult-
dc.titleDo patients with ulcerative colitis diagnosed at a young age have more severe disease activity than patients diagnosed when older?-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorLee J.H.-
dc.contributor.googleauthorCheon J.H.-
dc.contributor.googleauthorMoon C.M.-
dc.contributor.googleauthorPark J.J.-
dc.contributor.googleauthorHong S.P.-
dc.contributor.googleauthorKim T.I.-
dc.contributor.googleauthorKim W.H.-
dc.identifier.doi10.1159/000253850-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00774-
dc.contributor.localIdA01079-
dc.contributor.localIdA01390-
dc.contributor.localIdA01636-
dc.contributor.localIdA03231-
dc.contributor.localIdA04404-
dc.contributor.localIdA04030-
dc.relation.journalcodeJ00734-
dc.identifier.eissn1421-9867-
dc.identifier.pmid20110709-
dc.identifier.urlhttp://www.karger.com/Article/FullText/253850-
dc.subject.keywordAge-
dc.subject.keywordUlcerative colitis-
dc.subject.keywordPrognosis, ulcerative colitis-
dc.contributor.alternativeNameKim, Won Ho-
dc.contributor.alternativeNameKim, Tae Il-
dc.contributor.alternativeNameMoon, Chang Mo-
dc.contributor.alternativeNamePark, Jae Jun-
dc.contributor.alternativeNameLee, Jin Ha-
dc.contributor.alternativeNameCheon, Jae Hee-
dc.contributor.alternativeNameHong, Sung Pil-
dc.contributor.affiliatedAuthorKim, Won Ho-
dc.contributor.affiliatedAuthorKim, Tae Il-
dc.contributor.affiliatedAuthorMoon, Chang Mo-
dc.contributor.affiliatedAuthorPark, Jae Jun-
dc.contributor.affiliatedAuthorLee, Jin Ha-
dc.contributor.affiliatedAuthorHong, Sung Pil-
dc.contributor.affiliatedAuthorCheon, Jae Hee-
dc.citation.volume81-
dc.citation.number4-
dc.citation.startPage237-
dc.citation.endPage243-
dc.identifier.bibliographicCitationDIGESTION, Vol.81(4) : 237-243, 2010-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.