Cited 31 times in
Nonmuscle myosin II localization is regulated by JNK during Drosophila larval wound healing
DC Field | Value | Language |
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dc.contributor.author | 이향규 | - |
dc.date.accessioned | 2015-04-23T16:29:23Z | - |
dc.date.available | 2015-04-23T16:29:23Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100676 | - |
dc.description.abstract | We investigated cell shape changes during wound closure in the Drosophila larval epidermis. During reepithelialization, epidermal cells permanently change shape from pentagonal or hexagonal to irregular forms. This process requires zipper, a gene encoding the Drosophila nonmuscle myosin II heavy chain. Following wounding, myosin II is localized at the wound margin and at the rear end of individual cells located within several rows from the wound hole. The c-Jun N-terminal kinase (JNK) pathway is essential for this myosin II localization. These results suggest that not only the wound leading edge but also the cells lying distal to the leading edge cells actively participate in epithelial cell sheet migration during wound hole closure | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 656~661 | - |
dc.relation.isPartOf | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cell Shape | - |
dc.subject.MESH | Drosophila Proteins/metabolism* | - |
dc.subject.MESH | Drosophila melanogaster/cytology | - |
dc.subject.MESH | Drosophila melanogaster/metabolism | - |
dc.subject.MESH | Drosophila melanogaster/physiology* | - |
dc.subject.MESH | Epidermis/metabolism | - |
dc.subject.MESH | Epidermis/physiology* | - |
dc.subject.MESH | JNK Mitogen-Activated Protein Kinases/genetics | - |
dc.subject.MESH | JNK Mitogen-Activated Protein Kinases/metabolism* | - |
dc.subject.MESH | Larva/metabolism | - |
dc.subject.MESH | Larva/physiology | - |
dc.subject.MESH | Membrane Proteins/metabolism* | - |
dc.subject.MESH | Myosin Heavy Chains/metabolism* | - |
dc.subject.MESH | Wound Healing* | - |
dc.title | Nonmuscle myosin II localization is regulated by JNK during Drosophila larval wound healing | - |
dc.type | Article | - |
dc.contributor.college | College of Nursing (간호대학) | - |
dc.contributor.department | Dept. of Nursing Environment Systems (임상간호과학과) | - |
dc.contributor.googleauthor | Young-Chang Kwon | - |
dc.contributor.googleauthor | Seung Hee Baek | - |
dc.contributor.googleauthor | Hyangkyu Lee | - |
dc.contributor.googleauthor | Kwang-Min Choe | - |
dc.identifier.doi | 10.1016/j.bbrc.2010.02.047 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03282 | - |
dc.relation.journalcode | J00281 | - |
dc.identifier.eissn | 1090-2104 | - |
dc.identifier.pmid | 20153725 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0006291X10002585 | - |
dc.subject.keyword | Wound repair | - |
dc.subject.keyword | Zipper | - |
dc.subject.keyword | Actin cable | - |
dc.subject.keyword | Chemotaxis | - |
dc.contributor.alternativeName | Lee, Hyang Kyu | - |
dc.contributor.affiliatedAuthor | Lee, Hyang Kyu | - |
dc.citation.volume | 393 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 656 | - |
dc.citation.endPage | 661 | - |
dc.identifier.bibliographicCitation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.393(4) : 656-661, 2010 | - |
dc.identifier.rimsid | 37741 | - |
dc.type.rims | ART | - |
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