Cited 9 times in
Clinicopathologic report of uveal melanoma with persistent exudative retinal detachment after gamma knife radiosurgery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 고형준 | - |
dc.contributor.author | 권오웅 | - |
dc.contributor.author | 변석호 | - |
dc.contributor.author | 송원경 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 이성철 | - |
dc.date.accessioned | 2015-04-23T16:24:43Z | - |
dc.date.available | 2015-04-23T16:24:43Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0030-3755 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100534 | - |
dc.description.abstract | AIMS: Our purpose was to report the clinical and pathological findings from uveal melanoma patients with persistent exudative retinal detachment (RD) after Gamma Knife radiosurgery (GKR). METHODS: A retrospective review was performed. RESULTS: GKR was performed on 19 uveal melanoma patients from 2004 to 2006, and 5 of them developed persistent exudative RD. The mean initial largest basal tumor diameter in these 5 patients was 14.4 +/- 1.9 mm, and the mean tumor height was 9.2 +/- 1.0 mm. Marginal doses of 40-50 Gy radiation were administered. RD developed or had become aggravated an average of 3 (1-10) months after GKR. Two patients underwent enucleation, while the remaining 3 underwent tumor removal by endoresection with retinal reattachment surgery by vitrectomy and silicone oil tamponade. These procedures were undertaken an average of 6.3 (1.5-14) months after radiation and 3.3 (0.5-5) months after the onset or aggravation of RD. Histologically 4 tumors showed 50-100% necrosis without any mitotic activity. Thus local tumor control after GKR appeared sufficient regardless of RD. CONCLUSION: Aggravation or development of exudative RD after GKR does not necessarily entail treatment failure. Therefore, retinal reattachment surgery in persistent exudative RD may be an option to preserve the eye. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 16~21 | - |
dc.relation.isPartOf | OPHTHALMOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Exudates and Transudates* | - |
dc.subject.MESH | Eye Enucleation | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Melanoma/pathology | - |
dc.subject.MESH | Melanoma/surgery* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Necrosis | - |
dc.subject.MESH | Postoperative Complications/etiology* | - |
dc.subject.MESH | Postoperative Complications/pathology | - |
dc.subject.MESH | Postoperative Complications/surgery | - |
dc.subject.MESH | Radiosurgery/adverse effects* | - |
dc.subject.MESH | Retinal Detachment/etiology* | - |
dc.subject.MESH | Retinal Detachment/pathology | - |
dc.subject.MESH | Retinal Detachment/surgery | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Silicone Oils | - |
dc.subject.MESH | Uveal Neoplasms/pathology | - |
dc.subject.MESH | Uveal Neoplasms/surgery* | - |
dc.subject.MESH | Vitrectomy | - |
dc.title | Clinicopathologic report of uveal melanoma with persistent exudative retinal detachment after gamma knife radiosurgery | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | Song W.K. | - |
dc.contributor.googleauthor | Yang W.I. | - |
dc.contributor.googleauthor | Byeon S.H. | - |
dc.contributor.googleauthor | Koh H.J. | - |
dc.contributor.googleauthor | Kwon O.W. | - |
dc.contributor.googleauthor | Lee S.C. | - |
dc.identifier.doi | 10.1159/000233231 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00152 | - |
dc.contributor.localId | A00235 | - |
dc.contributor.localId | A01849 | - |
dc.contributor.localId | A02044 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A02873 | - |
dc.relation.journalcode | J02431 | - |
dc.identifier.eissn | 1423-0267 | - |
dc.identifier.pmid | 19684424 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/233231 | - |
dc.subject.keyword | Gamma Knife radiosurgery | - |
dc.subject.keyword | Uveal melanoma | - |
dc.subject.keyword | Retinal detachment | - |
dc.subject.keyword | Histopathology after radiation | - |
dc.contributor.alternativeName | Koh, Hyoung Jun | - |
dc.contributor.alternativeName | Kwon, Oh Woong | - |
dc.contributor.alternativeName | Byeon, Suk Ho | - |
dc.contributor.alternativeName | Song, Won Kyung | - |
dc.contributor.alternativeName | Yang, Woo Ick | - |
dc.contributor.alternativeName | Lee, Sung Chul | - |
dc.contributor.affiliatedAuthor | Koh, Hyoung Jun | - |
dc.contributor.affiliatedAuthor | Kwon, Oh Woong | - |
dc.contributor.affiliatedAuthor | Byeon, Suk Ho | - |
dc.contributor.affiliatedAuthor | Song, Won Kyung | - |
dc.contributor.affiliatedAuthor | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | Lee, Sung Chul | - |
dc.citation.volume | 224 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 16 | - |
dc.citation.endPage | 21 | - |
dc.identifier.bibliographicCitation | OPHTHALMOLOGICA, Vol.224(1) : 16-21, 2010 | - |
dc.identifier.rimsid | 36552 | - |
dc.type.rims | ART | - |
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