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Clinicopathologic report of uveal melanoma with persistent exudative retinal detachment after gamma knife radiosurgery

DC Field Value Language
dc.contributor.author고형준-
dc.contributor.author권오웅-
dc.contributor.author변석호-
dc.contributor.author송원경-
dc.contributor.author양우익-
dc.contributor.author이성철-
dc.date.accessioned2015-04-23T16:24:43Z-
dc.date.available2015-04-23T16:24:43Z-
dc.date.issued2010-
dc.identifier.issn0030-3755-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100534-
dc.description.abstractAIMS: Our purpose was to report the clinical and pathological findings from uveal melanoma patients with persistent exudative retinal detachment (RD) after Gamma Knife radiosurgery (GKR). METHODS: A retrospective review was performed. RESULTS: GKR was performed on 19 uveal melanoma patients from 2004 to 2006, and 5 of them developed persistent exudative RD. The mean initial largest basal tumor diameter in these 5 patients was 14.4 +/- 1.9 mm, and the mean tumor height was 9.2 +/- 1.0 mm. Marginal doses of 40-50 Gy radiation were administered. RD developed or had become aggravated an average of 3 (1-10) months after GKR. Two patients underwent enucleation, while the remaining 3 underwent tumor removal by endoresection with retinal reattachment surgery by vitrectomy and silicone oil tamponade. These procedures were undertaken an average of 6.3 (1.5-14) months after radiation and 3.3 (0.5-5) months after the onset or aggravation of RD. Histologically 4 tumors showed 50-100% necrosis without any mitotic activity. Thus local tumor control after GKR appeared sufficient regardless of RD. CONCLUSION: Aggravation or development of exudative RD after GKR does not necessarily entail treatment failure. Therefore, retinal reattachment surgery in persistent exudative RD may be an option to preserve the eye.-
dc.description.statementOfResponsibilityopen-
dc.format.extent16~21-
dc.relation.isPartOfOPHTHALMOLOGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHExudates and Transudates*-
dc.subject.MESHEye Enucleation-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMelanoma/pathology-
dc.subject.MESHMelanoma/surgery*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNecrosis-
dc.subject.MESHPostoperative Complications/etiology*-
dc.subject.MESHPostoperative Complications/pathology-
dc.subject.MESHPostoperative Complications/surgery-
dc.subject.MESHRadiosurgery/adverse effects*-
dc.subject.MESHRetinal Detachment/etiology*-
dc.subject.MESHRetinal Detachment/pathology-
dc.subject.MESHRetinal Detachment/surgery-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSilicone Oils-
dc.subject.MESHUveal Neoplasms/pathology-
dc.subject.MESHUveal Neoplasms/surgery*-
dc.subject.MESHVitrectomy-
dc.titleClinicopathologic report of uveal melanoma with persistent exudative retinal detachment after gamma knife radiosurgery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorSong W.K.-
dc.contributor.googleauthorYang W.I.-
dc.contributor.googleauthorByeon S.H.-
dc.contributor.googleauthorKoh H.J.-
dc.contributor.googleauthorKwon O.W.-
dc.contributor.googleauthorLee S.C.-
dc.identifier.doi10.1159/000233231-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00152-
dc.contributor.localIdA00235-
dc.contributor.localIdA01849-
dc.contributor.localIdA02044-
dc.contributor.localIdA02300-
dc.contributor.localIdA02873-
dc.relation.journalcodeJ02431-
dc.identifier.eissn1423-0267-
dc.identifier.pmid19684424-
dc.identifier.urlhttp://www.karger.com/Article/FullText/233231-
dc.subject.keywordGamma Knife radiosurgery-
dc.subject.keywordUveal melanoma-
dc.subject.keywordRetinal detachment-
dc.subject.keywordHistopathology after radiation-
dc.contributor.alternativeNameKoh, Hyoung Jun-
dc.contributor.alternativeNameKwon, Oh Woong-
dc.contributor.alternativeNameByeon, Suk Ho-
dc.contributor.alternativeNameSong, Won Kyung-
dc.contributor.alternativeNameYang, Woo Ick-
dc.contributor.alternativeNameLee, Sung Chul-
dc.contributor.affiliatedAuthorKoh, Hyoung Jun-
dc.contributor.affiliatedAuthorKwon, Oh Woong-
dc.contributor.affiliatedAuthorByeon, Suk Ho-
dc.contributor.affiliatedAuthorSong, Won Kyung-
dc.contributor.affiliatedAuthorYang, Woo Ick-
dc.contributor.affiliatedAuthorLee, Sung Chul-
dc.citation.volume224-
dc.citation.number1-
dc.citation.startPage16-
dc.citation.endPage21-
dc.identifier.bibliographicCitationOPHTHALMOLOGICA, Vol.224(1) : 16-21, 2010-
dc.identifier.rimsid36552-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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