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Comparison of temporal lobectomies of children and adults with intractable temporal lobe epilepsy

DC FieldValueLanguage
dc.contributor.author강훈철-
dc.contributor.author김동석-
dc.contributor.author김태승-
dc.contributor.author김흥동-
dc.contributor.author배선준-
dc.contributor.author이병인-
dc.contributor.author이윤진-
dc.contributor.author이준수-
dc.date.accessioned2015-04-23T16:22:08Z-
dc.date.available2015-04-23T16:22:08Z-
dc.date.issued2010-
dc.identifier.issn0256-7040-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100456-
dc.description.abstractINTRODUCTION: The aim of the study was to assess the difference in clinical characteristics and postsurgical outcomes between children and adults who have undergone temporal lobectomy (TL). MATERIALS AND METHODS: We retrospectively reviewed the medical records of 52 patients who had undergone TL between 2006 and 2008. Nineteen patients were classified as children (<or=18 years old), and 33 patients were classified as adults (>18 years old) according to the age when TL had been performed. RESULTS: Twelve of 19 (63.2%) children and 24 of 33 (72.7%) adults became seizure free. Rapid secondary generalization such as generalized tonic or tonic-clonic seizures showed a tendency to be more prominent in children (four of 19, 21.1%) than in adults (three of 33, 9.1%). Patients in childhood had significantly more multifocal discharges on interictal electroencephalography (EEG) (42.1%) compared to adults (15.2%, p = 0.014). The mean extent of surgical excision was 5.0 cm in children and 4.1 cm in adults (p = 0.001). The incidence of hippocampal sclerosis, the most common pathologic finding in the two groups, was 57.9% (11 of 19) in children and 78.8% (26 of 33) in adults. Malformations of cortical development were significantly more frequent in children (nine of 19, 47.4%) than in adults (seven of 33, 21.2%). Dual pathology was found in 31.6% of children and in 12.1% of adults. The intelligence quotient and memory quotient values in children with temporal lobe resection remained nearly steady during follow-up period without significant decline. CONCLUSION: Patients undergoing TL during childhood compared to during adulthood had distinctively different interictal EEG, resectional extents, and pathologic findings.-
dc.description.statementOfResponsibilityopen-
dc.format.extent177~183-
dc.relation.isPartOfCHILDS NERVOUS SYSTEM-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHAnterior Temporal Lobectomy*/adverse effects-
dc.subject.MESHAnterior Temporal Lobectomy*/methods-
dc.subject.MESHBrain/pathology-
dc.subject.MESHBrain/physiopathology-
dc.subject.MESHBrain/surgery-
dc.subject.MESHChild-
dc.subject.MESHEpilepsy, Generalized/pathology-
dc.subject.MESHEpilepsy, Generalized/physiopathology-
dc.subject.MESHEpilepsy, Generalized/surgery-
dc.subject.MESHEpilepsy, Temporal Lobe/pathology-
dc.subject.MESHEpilepsy, Temporal Lobe/physiopathology-
dc.subject.MESHEpilepsy, Temporal Lobe/surgery*-
dc.subject.MESHEpilepsy, Tonic-Clonic/pathology-
dc.subject.MESHEpilepsy, Tonic-Clonic/physiopathology-
dc.subject.MESHEpilepsy, Tonic-Clonic/surgery-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSeizures/pathology-
dc.subject.MESHSeizures/physiopathology-
dc.subject.MESHSeizures/surgery-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHYoung Adult-
dc.titleComparison of temporal lobectomies of children and adults with intractable temporal lobe epilepsy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorYun Jin Lee-
dc.contributor.googleauthorHoon-Chul Kang-
dc.contributor.googleauthorSun Joon Bae-
dc.contributor.googleauthorHeung Dong Kim-
dc.contributor.googleauthorJeong Tae Kim-
dc.contributor.googleauthorByung In Lee-
dc.contributor.googleauthorKyoung Heo-
dc.contributor.googleauthorJin Woo Jang-
dc.contributor.googleauthorDong Seok Kim-
dc.contributor.googleauthorTae Seung Kim-
dc.contributor.googleauthorJoon Soo Lee-
dc.identifier.doi10.1007/s00381-009-1015-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00102-
dc.contributor.localIdA00402-
dc.contributor.localIdA01071-
dc.contributor.localIdA01208-
dc.contributor.localIdA01795-
dc.contributor.localIdA02797-
dc.contributor.localIdA03026-
dc.contributor.localIdA03177-
dc.relation.journalcodeJ00525-
dc.identifier.eissn1433-0350-
dc.identifier.pmid19902220-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00381-009-1015-3-
dc.subject.keywordTemporal lobe epilepsy-
dc.subject.keyword Temporal lobectomy -
dc.subject.keywordChildren-
dc.subject.keyword Adults -
dc.contributor.alternativeNameKang, Hoon Chul-
dc.contributor.alternativeNameKim, Dong Seok-
dc.contributor.alternativeNameKim, Tai Seung-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameBai, Sun Joon-
dc.contributor.alternativeNameLee, Byung In-
dc.contributor.alternativeNameLee, Yun Jin-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthorKang, Hoon Chul-
dc.contributor.affiliatedAuthorKim, Dong Seok-
dc.contributor.affiliatedAuthorKim, Tai Seung-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorBai, Sun Joon-
dc.contributor.affiliatedAuthorLee, Byung In-
dc.contributor.affiliatedAuthorLee, Yun Jin-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.citation.volume26-
dc.citation.number2-
dc.citation.startPage177-
dc.citation.endPage183-
dc.identifier.bibliographicCitationCHILDS NERVOUS SYSTEM, Vol.26(2) : 177-183, 2010-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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