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Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida

DC Field Value Language
dc.contributor.author김응권-
dc.contributor.author김태임-
dc.date.accessioned2015-04-23T16:21:42Z-
dc.date.available2015-04-23T16:21:42Z-
dc.date.issued2010-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100443-
dc.description.abstractFour oligomeric procyanidins were isolated from the MeOH extracts of the leaves of Crataegus pinnatifida (Rosaceae). Investigation of collagenase and gelatinase inhibitory natural components afforded four oligomeric procyanidins. Of these, 2 and 3 exhibited collagenase inhibitory activity (IC(50)) at a concentration of less than 1 microM, and 3 showed gelatinases A and B inhibitory activity (IC(50)) at 0.4 and 2.3 microM, respectively.-
dc.description.statementOfResponsibilityopen-
dc.format.extent991~993-
dc.relation.isPartOfBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCollagenases/metabolism-
dc.subject.MESHCrataegus*-
dc.subject.MESHGelatinases/antagonists &inhibitors*-
dc.subject.MESHGelatinases/metabolism-
dc.subject.MESHHumans-
dc.subject.MESHMatrix MetalloproteinaseInhibitors*-
dc.subject.MESHPlant Extracts/chemistry*-
dc.subject.MESHPlant Extracts/isolation & purification-
dc.subject.MESHPlant Extracts/pharmacology*-
dc.subject.MESHPlant Leaves-
dc.titleIdentification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorHyung-In Moon-
dc.contributor.googleauthorTae-im Kim-
dc.contributor.googleauthorHyun-Soo Cho-
dc.contributor.googleauthorEung Kweon Kim-
dc.identifier.doi10.1016/j.bmcl.2009.12.059-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00831-
dc.contributor.localIdA01080-
dc.relation.journalcodeJ00326-
dc.identifier.eissn1464-3405-
dc.identifier.pmid20053563-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0960894X0901782X-
dc.subject.keywordCrataegus pinnatifida-
dc.subject.keywordOligomeric procyanidins-
dc.subject.keywordCollagenase-
dc.subject.keywordGelatinase-
dc.contributor.alternativeNameKim, Eung Kweon-
dc.contributor.alternativeNameKim, Tae Im-
dc.contributor.affiliatedAuthorKim, Eung Kweon-
dc.contributor.affiliatedAuthorKim, Tae Im-
dc.citation.volume20-
dc.citation.number3-
dc.citation.startPage991-
dc.citation.endPage993-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol.20(3) : 991-993, 2010-
dc.identifier.rimsid36491-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
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