1 576

Cited 22 times in

Papillary carcinoma located in the thyroid isthmus

Authors
 Yong Sang Lee  ;  Jong Ju Jeong  ;  Kee-Hyun Nam  ;  Woong Youn Chung  ;  Hang-Seok Chang  ;  Cheong Soo Park 
Citation
 WORLD JOURNAL OF SURGERY, Vol.34(1) : 36-39, 2010 
Journal Title
WORLD JOURNAL OF SURGERY
ISSN
 0364-2313 
Issue Date
2010
MeSH
Adult ; Aged ; Carcinoma, Papillary/diagnostic imaging ; Carcinoma, Papillary/pathology* ; Carcinoma, Papillary/surgery* ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Postoperative Complications ; ThyroidNeoplasms/diagnostic imaging ; ThyroidNeoplasms/pathology* ; ThyroidNeoplasms/surgery* ; Thyroidectomy ; Treatment Outcome ; Ultrasonography
Keywords
Thyroid Cancer ; Papillary Thyroid Carcinoma ; Total Thyroidectomy ; Papillary Carcinoma ; Lateral Neck
Abstract
BACKGROUND: The purpose of the present study was to evaluate the clinicopathologic characteristics and short-term outcomes of papillary thyroid carcinomas (PTC) located in the isthmus compared to tumors located in other thyroid regions, and to use those findings to establish a surgical strategy for treating these tumors. PATIENTS AND METHODS: Thyroidectomy was performed in 1,973 thyroid cancer patients in our hospital between January 2006 and December 2007. The patients were analyzed in two groups; group I, patients with tumors located in the isthmus (n = 181) and group II, patients with tumors located in other thyroid regions (n = 1,792). The clinicopathologic characteristics and short-term outcomes were compared between the two groups. RESULTS: The study groups were similar in terms of age and gender ratio. For groups I and II, respectively, the mean primary tumor size was 1.02 cm and 1.13 cm (p = 0.017), capsular invasion frequency was 70.2 and 60.8% (p = 0.008), and multifocality frequency was 48.6 and 39.8% (p = 0.006). In addition, central node involvement was 40.3 and 42.1% (p = 0.350), and lateral node involvement was 9.4 and 18.2% (p = 0.001). At the time of postoperative iodine-131 remnant ablation, 34.3% of group I patients and 38.0% of group II patients showed undetectable serum thyroglobulin concentrations. There were no significant differences in surgical complications between the two groups. CONCLUSIONS: Papillary thyroid carcinomas located in the isthmus was more likely to be associated with multiple foci in bilateral lobes and higher rates of capsular invasions than tumors in other thyroid regions. These findings indicate that total thyroidectomy is an appropriate initial surgical procedure for the isthmic PTC.
Full Text
http://link.springer.com/article/10.1007%2Fs00268-009-0298-6
DOI
10.1007/s00268-009-0298-6
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Nam, Kee Hyun(남기현) ORCID logo https://orcid.org/0000-0002-6852-1190
Park, Cheong Soo(박정수)
Lee, Yong Sang(이용상) ORCID logo https://orcid.org/0000-0002-8234-8718
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
Chung, Woong Youn(정웅윤)
Jeong, Jong Ju(정종주) ORCID logo https://orcid.org/0000-0002-4155-6035
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100421
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links