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가와사키병 환아에서 아스피린 치료 후 나타난 호산구증가증 1예

Other Titles
 Hypersensitivity reaction to aspirin accompanied by severe eosinophilia in a child with history of Kawasaki disease 
 설인숙  ;  최명현  ;  김민정  ;  김윤희  ;  이희선  ;  한윤기  ;  김기환  ;  김경원  ;  손명현  ;  김규언 
 Allergy Asthma & Respiratory Disease, Vol.2(2) : 142-145, 2014 
Journal Title
 Allergy Asthma & Respiratory Disease 
Issue Date
Drug hypersensitivity is one of drug adverse reactions that develop in susceptible patients following exposure to certain drugs and cannot be predicted from the known pharmacology of a drug. Severe hypersensitivity is associated with high morbidity and mortality. Although the issue of hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) has been largely investigated in adults, data related to NSAIDs hypersensitivity is insufficient in childhood. And in spite of the recommendation to avoid use of aspirin due to Reye syndrome in children, aspirin is one of major treatment along with intravenous immunoglobulin in Kawasaki disease. We report a case of a 10-month-old boy who underwent intravenous immunoglobulin and aspirin treatment for Kawasaki disease, and subsequently revealed severe leukocytosis and eosinophilia. To our knowledge, there have been no previous reports of aspirin-induced eosinophilia in Korea.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실)
Yonsei Authors
김경원(Kim, Kyung Won) ORCID logo https://orcid.org/0000-0003-4529-6135
김규언(Kim, Kyu Earn)
김기환(Kim, Ki Hwan)
김민정(Kim, Min Jung) ORCID logo https://orcid.org/0000-0002-5634-9709
김윤희(Kim, Yoon Hee) ORCID logo https://orcid.org/0000-0002-2149-8501
설인숙(Sol, In Suk) ORCID logo https://orcid.org/0000-0003-2470-9682
손명현(Sohn, Myung Hyun) ORCID logo https://orcid.org/0000-0002-2478-487X
이희선(Lee, Hee Seon)
한윤기(Han, Yoon Ki)
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