Fever-induced QTc prolongation and ventricular fibrillation in a healthy young man
Sun Min Lim ; Hui-Nam Pak ; Boyoung Joung ; Sung Soon Kim ; Moon-Hyoung Lee
Yonsei Medical Journal, Vol.52(6) : 1025~1027, 2011
Yonsei Medical Journal
Long QT syndrome is associated with lethal tachyarrhythmia that can lead to syncope, seizure, and sudden death. Congenital long QT syndrome is a genetic disorder, characterized by delayed cardiac repolarization and prolongation of the QT interval on the electrocardiogram (ECG). Type 2 congenital long QT is linked to mutations in the human ether a go-go-related gene (HERG). There are environmental triggers of adverse cardiac events such as emotional and acoustic stimuli, but fever can also be a potential trigger of life-threatening arrhythmias in long QT syndrome type 2 patients. Herein, we report a healthy young man who experienced fever-induced polymorphic ventricular tachycardia and QT interval prolongation.