YUHSpace

BROWSE

Export
7 624

Cited 21 times in

3-Diethylaminopropyl-bearing glycol chitosan as a protein drug carrier.

DC Field Value Language
dc.contributor.author오영택-
dc.date.accessioned2014-12-20T17:19:02Z-
dc.date.available2014-12-20T17:19:02Z-
dc.date.issued2011-
dc.identifier.issn0927-7765-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/94371-
dc.description.abstractPolysaccharidic nanogels were fabricated with bovine serum albumin (BSA) and a glycol chitosan (GCS) grafted with functional 3-diethylaminopropyl (DEAP) groups. These nanogels were investigated to evaluate their cellular uptake in HeLa cells and in vivo fate in nude mice tumor model. Unlike free BSA, GCS-g-DEAP/BSA nanogels improved cellular uptake of BSA. Furthermore, this system led to an enhanced blood circulation and a high accumulation of BSA in the tumor site. Our collective results strongly support that GCS-g-DEAP/BSA nanogel is a potential carrier system for high molecular weight proteins.-
dc.description.statementOfResponsibilityopen-
dc.format.extent585~590-
dc.relation.isPartOfCOLLOIDS AND SURFACES B-BIOINTERFACES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESH1-Propanol/chemistry*-
dc.subject.MESHAmines/chemistry*-
dc.subject.MESHAnimals-
dc.subject.MESHCattle-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHChitosan/chemistry*-
dc.subject.MESHDrugDelivery Systems*/methods-
dc.subject.MESHFemale-
dc.subject.MESHFlow Cytometry-
dc.subject.MESHHumans-
dc.subject.MESHMice-
dc.subject.MESHMice, Nude-
dc.subject.MESHModels, Molecular-
dc.subject.MESHMolecular Structure-
dc.subject.MESHNeoplasms/drugtherapy-
dc.subject.MESHPolyethylene Glycols/chemistry-
dc.subject.MESHPolyethyleneimine/chemistry-
dc.subject.MESHSerum Albumin, Bovine/chemistry*-
dc.title3-Diethylaminopropyl-bearing glycol chitosan as a protein drug carrier.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorHye Jung Baik-
dc.contributor.googleauthorNam Muk Oh-
dc.contributor.googleauthorYoung Taik Oh-
dc.contributor.googleauthorNa Young Yoo-
dc.contributor.googleauthorSo Young Park-
dc.contributor.googleauthorKyung Taek Oh-
dc.contributor.googleauthorYu Seok Youn-
dc.contributor.googleauthorEun Seong Lee-
dc.identifier.doi10.1016/j.colsurfb.2011.01.017-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02390-
dc.relation.journalcodeJ00627-
dc.identifier.eissn1873-4367-
dc.identifier.pmid21333505-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0927776511000373-
dc.subject.keywordPolysaccharidic nanogels-
dc.subject.keywordGlycol chitosan-
dc.subject.keywordBovine serum albumin-
dc.subject.keywordPh-sensitivity-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.affiliatedAuthorOh, Young Taik-
dc.rights.accessRightsnot free-
dc.citation.volume84-
dc.citation.number2-
dc.citation.startPage585-
dc.citation.endPage590-
dc.identifier.bibliographicCitationCOLLOIDS AND SURFACES B-BIOINTERFACES, Vol.84(2) : 585-590, 2011-
dc.identifier.rimsid27575-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Show simple item record Find it @ YMLIB

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

  • License
    sherpa_romeo
    sherpa_juliet

OAK

DSpace Software Copyright © 2002-2017 Duraspace Yonsei University Medical Library All right Reserves. / TEL:02-2228-2915 /
YUHSpace는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.

Browse

Links