Interproximal periodontal defect model in dogs: a pilot study.
U-W Jung ; Y-Y Chang ; S-H Choi ; K-S Cho ; C-S Kim ; Y-J Um
Oral Diseases, Vol.17(1) : 26~32, 2011
OBJECTIVE: This study aimed to evaluate the validity of a surgically created interproximal periodontal defect in dogs.
MATERIALS AND METHODS: Surgery was performed in the interproximal area between the maxillary second and third premolars in two beagle dogs. Following an incision and reflection of the gingival flap, a 3-mm wide and 5-mm high defect was prepared surgically at the interproximal area. A thorough root planing was performed and the flap was coronally positioned and sutured. The contra-lateral area was served as the control with no surgical intervention. After 8 weeks of healing, the animals were killed and the defect was analysed histometrically and radiographically.
RESULTS: The interproximal periodontal defect resembled a naturally occurring defect and mimicked a clinical situation. After healing, the defect showed limited bone (0.89±0.02mm) and cementum regeneration (1.50± 0.48mm).
CONCLUSIONS: Within the limitations of this pilot study, the interproximal periodontal defect showed limited bone and cementum regeneration. Thus, it can be considered as a standardized, reproducible defect model for testing new biomaterials.