Cited 0 times in

Clinical characteristics of acute hepatitis A complicated by acute kidney injury

Title
Clinical characteristics of acute hepatitis A complicated by acute kidney injury
Authors
Jung Hwan Yu;Ja Kyung Kim;Kwan Sik Lee;Chae Yoon Chon;Kwang-Hyub Han;Sang Hoon Ahn;Do Young Kim;Yong Han Paik;Jun yong Park
Issue Date
2012
Journal Title
Scandinavian Journal of Infectious Diseases
ISSN
0036-5548
Citation
Scandinavian Journal of Infectious Diseases, Vol.44(2) : 144~148, 2012
Abstract
BACKGROUND: The incidence of acute viral hepatitis A (AHA) in Korea is increasing rapidly. Additionally, we are encountering more cases with acute kidney injury (AKI), which was once regarded as a rare complication of AHA. Thus, we investigated recent aspects of the incidence and clinical characteristics of AHA complicated by AKI. METHODS: Patients diagnosed with AHA at 2 referral hospitals in Seoul during the period January 2006 to December 2009 were enrolled. RESULTS: Of 1025 patients, 71 (6.9%) had AKI. The incidence of AKI was 3.1% in 2006, 6.0% in 2007, 8.9% in 2008, and 6.9% in 2009. Patients with AKI were predominantly male, heavy alcohol drinkers, and smokers, and also had a higher rate of underlying hypertension than patients without AKI. At admission, patients with AKI had significantly higher white blood cell counts, prolonged prothrombin times, and elevated liver enzymes, including total and direct bilirubin, gamma-glutamyltransferase, and C-reactive protein. Additionally, patients with AKI had a higher peak total bilirubin level and lower initial serum albumin level than patients without AKI. CONCLUSION: Although most patients with AHA complicated by AKI recover with conservative treatment, we should pay particular attention to patients who have risk factors for AKI.
URI
http://informahealthcare.com/doi/abs/10.3109/00365548.2011.592145

http://ir.ymlib.yonsei.ac.kr/handle/22282913/91826
DOI
10.3109/00365548.2011.592145
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Biochemistry & Molecular Biology
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
사서에게 알리기
  feedback
Files in This Item:
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse