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Learning from HSV-infected mice as a model of Behçet's disease.

Authors
 S. Sohn ; E. Lee ; D. Bang 
Citation
 Clinical and Experimental Rheumatology, Vol.30(3 Suppl 72) : s96~s103, 2012 
Journal Title
 Clinical and Experimental Rheumatology 
ISSN
 0392-856X 
Issue Date
2012
Abstract
Several animal models of Behçet's disease (BD) have been proposed according to putative etiology. Among these models, the herpes simplex virus (HSV)-induced model produced the most similar disease attributes observe in patients. Inoculation of HSV type 1 to the scratched earlobe of mice produced the appropriate symptoms, including oral, genital, and skin ulcers, eye lesions, arthritis, and intestinal involvement. This HSV-induced BD model is the only continuously used model, to which various therapeutic modalities have been applied.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/90002
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Dermatology
Yonsei Authors
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Link
 http://www.clinexprheumatol.org/abstract.asp?a=5448
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