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Osteonecrosis of the jaw related to everolimus: a case report

Title
Osteonecrosis of the jaw related to everolimus: a case report
Authors
Dong Wook Kim;Young-Soo Jung;Hwi-Dong Jung;Hyung-Sik Park
Issue Date
2013
Journal Title
British Journal of Oral & Maxillofacial Surgery
ISSN
0266-4356
Citation
British Journal of Oral & Maxillofacial Surgery, Vol.51(8) : e302~e304, 2013
Abstract
Antiresorptive agent-related osteonecrosis of the jaw results in appreciable morbidity in affected patients. Nowadays many physicians prescribe an antiangiogenic agent for the management of malignant metastases. Everolimus is a serine-threonine kinase that acts as an inhibitor of mammalian target of rapamycin, which results in reduced growth of cells, angiogenesis, and survival of cells. We report the first case to our knowledge of osteonecrosis of the jaw that seemed to result from the additive effect of everolimus.
URI
http://www.sciencedirect.com/science/article/pii/S0266435613004269

http://ir.ymlib.yonsei.ac.kr/handle/22282913/88625
DOI
10.1016/j.bjoms.2013.09.008
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Oral and Maxillofacial Surgery
Yonsei Authors
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