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Osteonecrosis of the jaw related to everolimus: a case report

Authors
 Dong Wook Kim ; Young-Soo Jung ; Hwi-Dong Jung ; Hyung-Sik Park 
Citation
 British Journal of Oral & Maxillofacial Surgery, Vol.51(8) : e302~e304, 2013 
Journal Title
 British Journal of Oral & Maxillofacial Surgery 
ISSN
 0266-4356 
Issue Date
2013
Abstract
Antiresorptive agent-related osteonecrosis of the jaw results in appreciable morbidity in affected patients. Nowadays many physicians prescribe an antiangiogenic agent for the management of malignant metastases. Everolimus is a serine-threonine kinase that acts as an inhibitor of mammalian target of rapamycin, which results in reduced growth of cells, angiogenesis, and survival of cells. We report the first case to our knowledge of osteonecrosis of the jaw that seemed to result from the additive effect of everolimus.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/88625
DOI
10.1016/j.bjoms.2013.09.008
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Oral and Maxillofacial Surgery
Yonsei Authors
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Link
 http://www.sciencedirect.com/science/article/pii/S0266435613004269
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