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Topographical variation of macular choroidal thickness with myopia

Title
Topographical variation of macular choroidal thickness with myopia
Authors
Kwanghyun Lee;Junwon Lee;TaekJune Lee;Sung Chul Lee;Sun Young Park;Christopher S. Lee
Issue Date
2015
Journal Title
Acta Ophthalmologica
ISSN
1755-375X
Citation
Acta Ophthalmologica, Vol.93(6) : e469~e474, 2015
Abstract
PURPOSE: To study the association between topographical variation of choroidal thickness and myopic features in healthy eyes, using spectral domain optical coherence tomography (OCT). METHODS: Choroidal thickness was measured at the foveal centre (CTF) and 1.5 mm superiorly (CTS), inferiorly (CTI), nasally (CTN) and temporally (CTT) from the foveal centre, using enhanced depth imaging OCT. The temporal width of β zone of peripapillary atrophy (βPPA) was measured on infrared fundus images. The ratio of βPPA width to vertical disc diameter (PVDR) was calculated to correct retinal magnification. RESULTS: This study includes 85 eyes from 85 subjects who had a mean age of 53.9 ± 12.9 years, a mean axial length of 23.56 ± 0.82 mm, a mean refractive error of -0.14 ± 1.80 D, a mean βPPA width of 218.6 ± 181.3 μm and a mean PVDR of 0.13 ± 0.11. The CTF was thickest (266.4 ± 81.6), followed by CTS (256.2 ± 82.5 μm), CTT (251.7 ± 68.4 μm), CTI (247.7 ± 90.3 μm) and CTN (211.0 ± 76.5 μm). There were 31 eyes (36.5%) with CTT thicker than CTF. The CTT/CTF negatively correlated with refractive error (p = 0.012) and positively correlated with axial length (p = 0.031), βPPA width (p = 0.003) and PVDR (p = 0.006). CONCLUSIONS: There was a correlation between a thickened choroid, temporal to the foveal centre, with the severity of myopic components in normal eyes. Topographical changes might be induced by stretching of the choroid and sclera towards a temporal direction with eyeball elongation.
URI
http://onlinelibrary.wiley.com/doi/10.1111/aos.12701/abstract

http://ir.ymlib.yonsei.ac.kr/handle/22282913/141483
DOI
10.1111/aos.12701
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Ophthalmology
Yonsei Authors
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