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메토트렉세이트 사용 중 발생한 간을 침범한광범위큰B세포림프종 1예

Title
메토트렉세이트 사용 중 발생한 간을 침범한광범위큰B세포림프종 1예
Other Titles
A Case of Diffuse Large B-cell Lymphoma with Liver Involvement in a 67-Year-Old Woman Given Methotrexate for Rheumatoid Arthritis
Authors
천재영;최희승;김유리;이민영;조미옥;이서희;조세희
Issue Date
2015
Journal Title
Korean Journal of Medicine (대한내과학회지)
ISSN
1226-329X
Citation
Korean Journal of Medicine (대한내과학회지), Vol.88(6) : 715~718, 2015
Abstract
Prolonged inflammation or immunosuppression may cause lymphoproliferative disorders (LPD). Rheumatoid arthritis (RA) itself causes LPD. The immunosuppressive drug methotrexate (MTX) is used widely to treat RA, and is also related to the development of lymphoma. Although the detailed pathogenesis and association are still controversial, care is needed when managing patients with RA treated with MTX. Many reports indicate that discontinuing MTX can induce the regression of LPD. Here, we describe a case of diffuse large B-cell lymphoma that presented with liver involvement in a 67-year-old woman who had used MTX for RA for 15 years.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/140858
DOI
10.3904/kjm.2015.88.6.715
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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