Browsing by Yonsei Author : Lee, Sang-Won

eperson profile image
Name :
Lee, Sang-Won [이상원]
orcid http://orcid.org/0000-0002-8038-3341
Department :
College of Medicine (의과대학) - Dept. of Internal Medicine (내과학교실)
Scopus ID :
Scopus (36072602700)

교수 기본정보

세부 전공
류마티스학 (ANCA연관혈관염)
이메일
sangwonlee@yuhs.ac

실험실 기본정보

이름
자가면역 혈관염 클리닉
위치
류마티스내과 외래 65번 진료실 & ABMRC 201호
구분
Wet Lab (20%), Dry Lab (80%)

연구소개

연구 분야
연구 내용
1) ANCA연관 혈관염 코호트의 경쟁력
 ANCA연관혈관염 코호트는 우리나라에서 유일한 코호트임
 ANCA연관혈괌염 전향적 코호트에는 200여명의 환자가 포함
 후향적 코호트에는 300명 이상의 환자가 포함

2) 전향적 코호트 환자 연구
 ANCA연관혈관염 진단 당시의 임상데이터와 혈액 검체를 이용한 연구
 혈액 검체에서 혈청과 말초혈액단핵구세포(PBMC) 분리와 보관
 혈청과 말초혈액단핵구세포(PBMC)를 이용해서 ANCA연관혈관염의 활성 및 예후를 예측하는 바이오마커를 발굴함

3) 후향적 코호트 환자 연구
ANCA연관혈관염 환자의 진단 시 그리고 추적관찰 기간 동안의 축적된 임상데이터를 이용해서 예후를 예측하는 지표(index)를 발굴함

학생 참여 정보

학생들이 참여하면 좋을 연구
  • - 이미 ANCA연관혈관염 코호트 임상데이터와 혈액 검체는 확보되어 있음.
  • - 학생과 ANCA연관혈관염의 병리기전과 증상 예후 등에 대해서 공부와 토의를 진행.
  • - 현재까지 알려진 ANCA연관혈관염 활성과 예후 예측 지표 및 바이오마커의 unmet need에 대해서 조사 후 토의 진행.
  • - 새로운 후보 지표 및 바이오마커 결정 후 연구를 통해서 임상적 의미를 검증하고 연구 논문을 작성하고 발표함
학생 참여 시 사용하게 되는 장비 및 프로그램
  • - 임상데이터의 분석을 위한 통계 프로그램과 방법 숙지
  • - 바이오마커 발굴의 경우, ex vivo (혈청 및 말초혈액단핵구세포) 바이오마커 농도 측정의 참관 (ELISA and FACS) 및 결과 분석을 위한 통계 프로그램과 방법 숙지
참여 전 준비사항
  • IRB 연구자 등록을 위한 IRB 연구자 교육 수료

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Showing results 1 to 50 of 316

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Issue DateTitleJournal Title
2025Rapamycin Modulates the Polarisation of CD4+ T Cells Towards TH1 Cells in Patients with Active Granulomatosis with Polyangiitis and Microscopic Polyangiitis JOURNAL OF CLINICAL MEDICINE
2025Plasma Exchange as an Adjunctive Therapeutic Option for Severe and Refractory Antineutrophil Cytoplasmic Antibody-Negative Microscopic Polyangiitis and Granulomatosis with Polyangiitis MEDICINA-LITHUANIA
2025Utility of serum cystatin C measured at diagnosis in evaluating cross-sectional activity and predicting all-cause mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitisCLINICAL RHEUMATOLOGY
2025Initial Circulating CD138 Predicts End-Stage Kidney Disease in Patients with Microscopic Polyangiitis YONSEI MEDICAL JOURNAL
2025Is Chest Imaging Alone Adequate for Diagnosing Interstitial Lung Disease in Microscopic Polyangiitis Based on the 2022 Criteria? YONSEI MEDICAL JOURNAL
2025Lower Myeloperoxidase-ANCA Titres at Diagnosis Are Associated with End-Stage Kidney Disease Progression During Follow-Up in Rituximab-Treated Patients with Microscopic PolyangiitisMEDICINA-LITHUANIA
2025Development of a new scoring system for predicting recurrent thrombosis in patients with antiphospholipid syndromeADVANCES IN RHEUMATOLOGY
2025Clinical Implications of Point-of-Care Measurement of Adalimumab Concentration and Anti-Adalimumab Antibodies in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2025Application of the 2023 ACR/EULAR antiphospholipid syndrome classification criteria to patients fulfilling the 2006 revised Sapporo criteriaCLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2025A new formula consisting of the five-factor score and earliest vasculitis damage index at diagnosis for predicting poor outcomes of antineutrophil cytoplasmic antibody-associated vasculitis FRONTIERS IN MEDICINE
2025Unraveling the differential diagnosis of hyperferritinemia: insights from a retrospective study at a tertiary care hospitalPOSTGRADUATE MEDICAL JOURNAL
2025Impact of Early MPO-ANCA Positivity on Unique Clinical Features in Korean Patients with EGPA: A Single-Centre Cohort Study MEDICINA-LITHUANIA
2025Clinical Significance of Peripheral Arterial Disease Evaluation in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis MEDICINA-LITHUANIA
2025Adjusted Global Antiphospholipid Syndrome Score Is Associated with End-Stage Kidney Disease in Patients with ANCA-Associated Vasculitis: A Single-Centre Pilot Study YONSEI MEDICAL JOURNAL
2025Clinical perspective on serum periostin in antineutrophil-cytoplasmic antibody-associated vasculitis KOREAN JOURNAL OF INTERNAL MEDICINE
2025Immunologic Response and Effects of COVID-19 Vaccines in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis YONSEI MEDICAL JOURNAL
2025Overlap Syndrome of Primary Sjögren Syndrome with Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Based on the American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR) Criteria DIAGNOSTICS
2025Validation of the 2022 ACR/EULAR classification criteria for giant cell arteritis in Korean patients with giant cell arteritisMODERN RHEUMATOLOGY
2025Serum Wnt3A levels are significantly associated with cross-sectional vasculitis activity and end-stage kidney disease during follow-up of patients with antineutrophil cytoplasmic antibody-associated vasculitisCLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2025Clinical Utility of Serum sCD200/sCD200R Ratios in Predicting Current Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis JOURNAL OF CLINICAL MEDICINE
2025Remnant Cholesterol Levels at Diagnosis May Predict Acute Coronary Syndrome Occurrence During Follow-Up in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis JOURNAL OF CLINICAL MEDICINE
2025Circulating GDF15 May Estimate Vasculitis Activity and Predict Poor Outcomes During the Disease Course of ANCA-Associated Vasculitis JOURNAL OF CLINICAL MEDICINE
2025Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis FRONTIERS IN MOLECULAR BIOSCIENCES
2025Prediction potential of serum sulfatide levels at diagnosis for end-stage kidney disease progression in ANCA-associated vasculitis MEDICINE
2025A New Formula Consisting of the Initial Independent Predictors of All-Cause Mortality Derived from a Single-Centre Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis JOURNAL OF CLINICAL MEDICINE
2025Reclassification of the overlap syndrome of Behçet’s disease and antineutrophil cytoplasmic antibody-associated vasculitis in patients with Behçet’s disease KOREAN JOURNAL OF INTERNAL MEDICINE
2024Serum Soluble Receptors for Advanced Glycation End-Products May Predict Mortality in Microscopic Polyangiitis and Granulomatosis with Polyangiitis YONSEI MEDICAL JOURNAL
2024Serum Glial Fibrillary Acidic Protein Can Predict Cross-Sectional Vasculitis Activity by Reflecting Renal Involvement in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis MEDICINA-LITHUANIA
2024Hypophysitis and central nervous system involvement in association with Sjögren's syndrome along with hypoparathyroidism: a case report BMC NEUROLOGY
2024Serum syndecan1 has the potential to reflect activity at diagnosis and predict death during follow-up in patients with ANCA-associated vasculitis ARTHRITIS RESEARCH & THERAPY
2024Clinical Significance of Overlap Syndrome of Histologically Confirmed Lupus Nephritis with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis JOURNAL OF CLINICAL MEDICINE
2024Application of the 2022 ACR/EULAR criteria for Takayasu arteritis to previously diagnosed patients based on the 1990 ACR criteriaMODERN RHEUMATOLOGY
2024Circulating Malondialdehyde Is a Potential Biomarker for Predicting All-Cause Mortality during Follow-Up by Reflecting Comprehensive Inflammation at Diagnosis in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis MEDICINA-LITHUANIA
2024The Clinical Utility of Serum Alpha-1-Acid Glycoprotein in Reflecting the Cross-Sectional Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single-Centre Retrospective Study MEDICINA-LITHUANIA
2024The monocyte-to-high-density lipoprotein-cholesterol ratio at diagnosis is associated with cerebrovascular accident during follow-up in patients with antineutrophil cytoplasmic antibody-associated vasculitis Journal of Rheumatic Diseases
2024Overlap syndrome of systemic sclerosis with antineutrophil cytoplasmic antibody-associated vasculitis according to 2022 ACR/EULAR criteria KOREAN JOURNAL OF INTERNAL MEDICINE
2024First-year cumulative myeloperoxidase-ANCA titres are associated with all-cause mortality in patients with microscopic polyangiitis CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2024Earliest total vascular damage index scores independently predict all-cause mortality in patients with ANCA-associated vasculitis CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2024Chemokine expression in sera of patients with microscopic polyangiitis and granulomatosis with polyangiitis SCIENTIFIC REPORTS
2024Alcoholic Liver Disease/Nonalcoholic Fatty Liver Disease Index at Diagnosis Is Associated with All-Cause Mortality during Follow-Up in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis MEDICINA-LITHUANIA
2024Circulating cold-inducible RNA-binding protein levels in microscopic polyangiitis and granulomatosis with polyangiitis : Correlation with disease activityZEITSCHRIFT FUR RHEUMATOLOGIE
2024Birmingham vasculitis activity score and the short form 36-item health survey predict current depressive disorders in patients with antineutrophil cytoplasmic antibody-associated vasculitis during the SARS-CoV-2 pandemic ZEITSCHRIFT FUR RHEUMATOLOGIE
2024Clinical association of health-related quality of life and mortality in an antineutrophil cytoplasmic antibody-associated vasculitis cohortSEMINARS IN ARTHRITIS AND RHEUMATISM
2024Antineutrophil cytoplasmic antibody-associated vasculitis classification by cluster analysis based on clinical phenotypes: a single-center retrospective cohort studyCLINICAL RHEUMATOLOGY
2023Clinical implications of peripheral eosinophil count at diagnosis in patients newly diagnosed with microscopic polyangiitis and granulomatosis with polyangiitis ARTHRITIS RESEARCH & THERAPY
2023IL-6 Receptor Expression on the Surface of T Cells and Serum Soluble IL-6 Receptor Levels in Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis JOURNAL OF CLINICAL MEDICINE
2023Phonozen-mediated photodynamic therapy comparing two wavelengths in a mouse model of peritoneal carcinomatosisPHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
2023Prevalence, clinical significance, and persistence of autoantibodies in COVID-19 VIROLOGY JOURNAL
2023Overlap Syndrome Consisting of Polymyositis/Dermatomyositis and ANCA-Associated Vasculitis According to the 2022 ACR/EULAR Criteria for Vasculitis: A Korean Single-Centre Study JOURNAL OF CLINICAL MEDICINE
2023Soluble triggering receptor expressed on myeloid cell-1 reflects the cross-sectional activity of microscopic polyangiitis and granulomatosis with polyangiitis HELIYON

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