| 2024 | ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation
| ELIFE |
| 2024 | ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells
| AUTOPHAGY |
| 2023 | Impaired TFEB activation and mitophagy as a cause of PPP3/calcineurin inhibitor-induced pancreatic beta-cell dysfunction
| AUTOPHAGY |
| 2022 | Essential role of lysosomal Ca2+-mediated TFEB activation in mitophagy and functional adaptation of pancreatic β-cells to metabolic stress
| AUTOPHAGY |
| 2022 | SMP30-mediated synthesis of vitamin C activates the liver PPARα/FGF21 axis to regulate thermogenesis in mice
| EXPERIMENTAL AND MOLECULAR MEDICINE |
| 2022 | Cell non-autonomous effect of hepatic growth differentiation factor 15 on the thyroid gland
| FRONTIERS IN ENDOCRINOLOGY |
| 2022 | Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
| CANCER COMMUNICATIONS |
| 2022 | A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome | HEPATOLOGY |
| 2022 | Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
| NATURE GENETICS |
| 2022 | Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21
| FRONTIERS IN IMMUNOLOGY |
| 2022 | Lysosomal Ca 2+-mediated TFEB activation modulates mitophagy and functional adaptation of pancreatic β-cells to metabolic stress
| NATURE COMMUNICATIONS |
| 2022 | Suppressive Effect of Autocrine FGF21 on Autophagy-Deficient Hepatic Tumorigenesis
| FRONTIERS IN ONCOLOGY |
| 2022 | Current Status of Autophagy Enhancers in Metabolic Disorders and Other Diseases
| FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY |
| 2021 | TFEB-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response | NATURE METABOLISM |
| 2021 | GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS |
| 2021 | TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium | AUTOPHAGY |
| 2021 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) | AUTOPHAGY |
| 2021 | An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer
| NATURE COMMUNICATIONS |
| 2020 | Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics
| FRONTIERS IN IMMUNOLOGY |
| 2020 | Identification of type 2 diabetes loci in 433,540 East Asian individuals
| NATURE |
| 2020 | Innate immune receptors in type 1 diabetes: the relationship to cell death-associated inflammation | BIOCHEMICAL SOCIETY TRANSACTIONS |
| 2020 | SGLT2 Inhibition Modulates NLRP3 Inflammasome Activity via Ketones and Insulin in Diabetes With Cardiovascular Disease
| NATURE COMMUNICATIONS |
| 2020 | Autophagy Induction Can Regulate Skin Pigmentation by Causing Melanosome Degradation in Keratinocytes and Melanocytes | PIGMENT CELL & MELANOMA RESEARCH |
| 2020 | Mitochondrial Ca2+ Uptake Relieves Palmitate-Induced Cytosolic Ca2+ Overload in MIN6 Cells
| MOLECULES AND CELLS |
| 2019 | β-cell autophagy: Mechanism and role in β-cell dysfunction
| Molecular Metabolism |
| 2019 | Autophagy in FOXD1 stroma-derived cells regulates renal fibrosis through TGF-β and NLRP3 inflammasome pathway | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2019 | Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-β and NLRP3 inflammasome signaling pathway
| CELL DEATH & DISEASE |
| 2019 | Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia
| SCIENTIFIC REPORTS |
| 2018 | Amelioration of obesity-induced diabetes by a novel autophagy enhancer
| CELL STRESS |
| 2018 | Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population | DIABETES |
| 2018 | Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches
| FRONTIERS IN ENDOCRINOLOGY |
| 2018 | The Role of Autophagy in Systemic Metabolism and Human-Type Diabetes
| MOLECULES AND CELLS |
| 2018 | Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice
| SCIENTIFIC REPORTS |
| 2018 | A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes
| NATURE COMMUNICATIONS |
| 2017 | Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis.
| PLOS ONE |
| 2017 | Alterations in Gut Microbiota and Immunity by Dietary Fat.
| YONSEI MEDICAL JOURNAL |
| 2017 | Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition | AUTOPHAGY |
| 2016 | Extracellular Vesicles as Messengers Between Hepatocytes and Macrophages in Nonalcoholic Steatohepatitis | GASTROENTEROLOGY |
| 2016 | Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice
| AUTOPHAGY |
| 2016 | Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance | ARCHIVES OF PHARMACAL RESEARCH |
| 2016 | CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
| SCIENTIFIC REPORTS |
| 2016 | Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis | AUTOPHAGY |
| 2016 | Role of mitochondrial function in cell death and body metabolism | FRONTIERS IN BIOSCIENCE-LANDMARK |
| 2016 | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
| NATURE COMMUNICATIONS |
| 2016 | The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression
| PLOS ONE |
| 2016 | Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesion
| BIOCHEMICAL JOURNAL |
| 2016 | Autophagy is a major regulator of beta cell insulin homeostasis | DIABETOLOGIA |
| 2015 | Effect of mitochondrial stress on systemic metabolism | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES |
| 2015 | Age-dependent gait abnormalities in mice lacking the Rnf170 gene linked to human autosomal-dominant sensory ataxia | HUMAN MOLECULAR GENETICS |
| 2015 | FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs
| JOURNAL OF ENDOCRINOLOGY |
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