2 417

Cited 4 times in

Association Between Urine Cotinine Levels and Bone Mineral Density in Lumbar Spine and Femoral Neck Among Adult Males

DC Field Value Language
dc.contributor.author김긍년-
dc.contributor.author신동아-
dc.contributor.author윤도흠-
dc.contributor.author하윤-
dc.date.accessioned2015-01-06T17:25:49Z-
dc.date.available2015-01-06T17:25:49Z-
dc.date.issued2014-
dc.identifier.issn0362-2436-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99964-
dc.description.abstractSTUDY DESIGN: Cross-sectional study. OBJECTIVE: To investigate an association between tobacco exposure as determined by urine cotinine and bone mineral density (BMD) in femoral neck and lumbar spine. SUMMARY OF BACKGROUND DATA: Loss of BMD is 1 of the major causes of spine and femoral neck fractures in the elderly population. There is limited literature on risk factors to loss of BMD, in particular, among males. METHODS: We analyzed data of 770 males older than 30 years, which were collected from the cross-sectional Fifth Korea National Health and Nutrition Examination Survey, with t tests, analysis of variance, and multiple linear regressions. RESULTS: The means of femoral neck BMD (T score) significantly decreased with increasing age, -0.08, -0.63, and -1.49 in males aged 30 to 40 years, 50 to 69 years, and 70 to 95 years, respectively (P < 0.001). The same trend was observed in lumbar spine BMD. Although education (P < 0.001) and income (P = 0.021) were associated with femoral neck T score, only education (P = 0.034) was associated with lumbar spine T score. The group who had urine cotinine level of more than 10 μg/mL (active smokers or nonsmokers who were exposed to second-hand smoking) had lower femoral neck T score (-0.43 ± 0.98) than the group who had cotinine level of 10 μg/mL or less (-0.33 ± 0.89) (P = 0.114). In the multiple linear regressions, age, urine cotinine level, and body mass index were statistically related to femoral neck and lumbar spine T score. CONCLUSION: Our findings suggest that tobacco exposure by active or passive smoking and lower body mass index seem to exert a negative effect on femoral neck and lumbar spine BMD.-
dc.description.statementOfResponsibilityopen-
dc.format.extent311~317-
dc.relation.isPartOfSPINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHBody Mass Index-
dc.subject.MESHBone Density/physiology*-
dc.subject.MESHCotinine/urine*-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemur Neck/diagnostic imaging*-
dc.subject.MESHHumans-
dc.subject.MESHLumbar Vertebrae/diagnostic imaging*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNutrition Surveys-
dc.subject.MESHRadiography-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRisk Factors-
dc.titleAssociation Between Urine Cotinine Levels and Bone Mineral Density in Lumbar Spine and Femoral Neck Among Adult Males-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학)-
dc.contributor.googleauthorSungkyu Lee-
dc.contributor.googleauthorDo Heum Yoon-
dc.contributor.googleauthorKeung Nyun Kim-
dc.contributor.googleauthorDong Ah Shin-
dc.contributor.googleauthorYoon Ha-
dc.identifier.doi10.1097/BRS.0000000000000138-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00331-
dc.contributor.localIdA02092-
dc.contributor.localIdA02546-
dc.contributor.localIdA04255-
dc.relation.journalcodeJ02674-
dc.identifier.eissn1528-1159-
dc.identifier.pmid24299722-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00007632-201402150-00015&LSLINK=80&D=ovft-
dc.subject.keywordsmoking-
dc.subject.keywordurine cotinine-
dc.subject.keywordfemoral neck-
dc.subject.keywordlumbar spine-
dc.subject.keywordbone mineral density-
dc.contributor.alternativeNameKim, Keung Nyun-
dc.contributor.alternativeNameShin, Dong A-
dc.contributor.alternativeNameYoon, Do Heum-
dc.contributor.alternativeNameHa, Yoon-
dc.contributor.affiliatedAuthorKim, Keung Nyun-
dc.contributor.affiliatedAuthorShin, Dong A-
dc.contributor.affiliatedAuthorYoon, Do Heum-
dc.contributor.affiliatedAuthorHa, Yoon-
dc.rights.accessRightsfree-
dc.citation.volume39-
dc.citation.number4-
dc.citation.startPage311-
dc.citation.endPage317-
dc.identifier.bibliographicCitationSPINE, Vol.39(4) : 311-317, 2014-
dc.identifier.rimsid53917-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.