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Does the type of anesthetic agent affect remifentanil effect-site concentration for preventing endotracheal tube-induced cough during anesthetic emergence? Comparison of propofol, sevoflurane, and desflurane

DC FieldValueLanguage
dc.contributor.author이정림-
dc.contributor.author최승호-
dc.contributor.author최용선-
dc.contributor.author이반-
dc.contributor.author이재훈-
dc.date.accessioned2015-01-06T17:23:34Z-
dc.date.available2015-01-06T17:23:34Z-
dc.date.issued2014-
dc.identifier.issn0952-8180-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99894-
dc.description.abstractSTUDY OBJECTIVE: To investigate whether the type of anesthetic agent administered affects the antitussive effect of remifentanil. DESIGN: Prospective randomized study. SETTING: Operating room of a university hospital. PATIENTS: 78 ASA physical status 1 and 2 women, aged 20 to 65 years, who were scheduled to undergo a thyroidectomy. INTERVENTIONS: Patients were randomly assigned to three groups to receive anesthesia with propofol (Group P), sevoflurane (Group S), or desflurane (Group D). The main anesthetics were titrated to maintain a target Bispectral Index for hypnosis of 40 to 60. Remifentanil was administered via effect-site target-controlled infusion (TCI). To determine the effective remifentanil effect-site concentration (Ce) to suppress coughing in each group, the up-and-down sequential allocation design was used. MEASUREMENTS: The half maximal effective concentration (EC50) values of remifentanil for preventing coughing in the groups were estimated using isotonic regression and compared among the groups. MAIN RESULTS: The EC50 of remifentanil for cough suppression in Group P [1.60 ng/mL (98.3% CI, 0.92-1.75 ng/mL)] was statistically lower than in Group D [1.96 ng/mL (98.3% CI, 1.81-2.50 ng/mL)]. The EC50 in Group S was 1.75 ng/mL (98.3% CI, 1.39-2.13 ng/mL), which was higher than in Group P and lower than in Group D, but did not differ significantly from either group. CONCLUSIONS: Remifentanil administration for cough suppression during emergence should be customized to the anesthetic agent.-
dc.description.statementOfResponsibilityopen-
dc.format.extent466~474-
dc.relation.isPartOfJournal of Clinical Anesthesia-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleDoes the type of anesthetic agent affect remifentanil effect-site concentration for preventing endotracheal tube-induced cough during anesthetic emergence? Comparison of propofol, sevoflurane, and desflurane-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorJae Hoon Lee-
dc.contributor.googleauthorSeung Ho Choi-
dc.contributor.googleauthorYong Seon Choi-
dc.contributor.googleauthorBahn Lee-
dc.contributor.googleauthorShi Joon Yang-
dc.contributor.googleauthorJeong-Rim Lee-
dc.identifier.doi10.1016/j.jclinane.2014.02.002-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03098-
dc.contributor.localIdA04119-
dc.contributor.localIdA02790-
dc.contributor.localIdA04101-
dc.contributor.localIdA03092-
dc.relation.journalcodeJ01315-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0952818014001081-
dc.contributor.alternativeNameLee, Jeong Rim-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.alternativeNameChoi, Yong Seon-
dc.contributor.alternativeNameLee, Bahn-
dc.contributor.alternativeNameLee, Jae Hoon-
dc.contributor.affiliatedAuthorLee, Jeong Rim-
dc.contributor.affiliatedAuthorChoi, Yong Seon-
dc.contributor.affiliatedAuthorLee, Bahn-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.contributor.affiliatedAuthorLee, Jae Hoon-
dc.rights.accessRightsfree-
dc.citation.volume26-
dc.citation.number6-
dc.citation.startPage466-
dc.citation.endPage474-
dc.identifier.bibliographicCitationJournal of Clinical Anesthesia, Vol.26(6) : 466-474, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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