Cited 0 times in
비스포스포네이트의 치료 기간
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이유미 | - |
dc.date.accessioned | 2015-01-06T17:22:26Z | - |
dc.date.available | 2015-01-06T17:22:26Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1226-329X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99858 | - |
dc.description.abstract | Large, randomized, controlled trials have demonstrated the efficacy of bisphosphonates (BP) in terms of improving bone mineral density (BMD) and reducing fracture risk. Consequently, bisphosphonates are used widely in the treatment of osteoporosis. Recently, however, several safety issues regarding the long-term use of BP, especially BP-related osteonecrosis of the jaws and atypical fractures, have been noted and have emerged as a limitation of their clinical use. Although the absolute risk is very small, the risks could increase with the long-term use of BP. The anti-fracture efficacy of BP is not sustained after treatment for 5-10 years. Therefore, recommendations suggest that a drug holiday be considered after 5 years of treatment for patients at low risk of fracture. However, as the individual fracture risk varies, the treatment duration should be based on individual clinical risk factors and bone metabolism status. Moreover, recommendations regarding monitoring after discontinuing and reinitiating BP await further studies. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 151~155 | - |
dc.relation.isPartOf | Korean Journal of Medicine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 비스포스포네이트의 치료 기간 | - |
dc.title.alternative | Duration of Bisphosphonate Treatment | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | 김경민 | - |
dc.contributor.googleauthor | 이유미 | - |
dc.identifier.doi | 10.3904/kjm.2014.87.2.151 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03012 | - |
dc.relation.journalcode | J02059 | - |
dc.subject.keyword | Bisphosphonates | - |
dc.subject.keyword | Osteoporosis | - |
dc.subject.keyword | Safety | - |
dc.subject.keyword | Drug holiday | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.citation.volume | 87 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 151 | - |
dc.citation.endPage | 155 | - |
dc.identifier.bibliographicCitation | Korean Journal of Medicine, Vol.87(2) : 151-155, 2014 | - |
dc.identifier.rimsid | 53842 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.