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Understanding the Complexity of the Immune System during Pregnancy

Authors
 Karen Racicot  ;  Ja-Young Kwon  ;  Paulomi Aldo  ;  Michelle Silasi  ;  Gil Mor 
Citation
 American Journal of Reproductive Immunology, Vol.72(2) : 107-116, 2014 
Journal Title
 American Journal of Reproductive Immunology 
ISSN
 1046-7408 
Issue Date
2014
MeSH
Bacterial Infections/immunology* ; Bacterial Infections/microbiology ; Female ; Fetus/immunology* ; Fetus/microbiology ; Fetus/virology ; Humans ; Immune System* ; Immune Tolerance ; Maternal-Fetal Exchange/immunology ; Obstetric Labor, Premature/immunology ; Obstetric Labor, Premature/microbiology ; Obstetric Labor, Premature/virology ; Placenta/immunology* ; Placenta/microbiology ; Placenta/virology ; Pregnancy ; Virus Diseases/immunology* ; Virus Diseases/microbiology
Keywords
Immune regulation ; macrophages ; pregnancy ; trophoblast
Abstract
Progress in our understanding of the role of the maternal immune system during healthy pregnancy will help us better understand the role of the immune system in adverse pregnancy outcomes. In this review, we discuss our present understanding of the ‘immunity of pregnancy’ in the context of the response to cervical and placental infections and how these responses affect both the mother and the fetus. We discuss novel and challenging concepts that help explain the immunological aspects of pregnancy and how the mother and fetus respond to infection.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/aji.12289/abstract
DOI
10.1111/aji.12289
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ja Young(권자영) ORCID logo https://orcid.org/0000-0003-3009-6325
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99843
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