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Cited 16 times in

Prognostic Factors for Urachal Cancer: A Bayesian Model-Averaging Approach

DC FieldValueLanguage
dc.contributor.author양승철-
dc.contributor.author이주용-
dc.contributor.author조강수-
dc.contributor.author최영득-
dc.contributor.author함원식-
dc.contributor.author홍성준-
dc.contributor.author권종규-
dc.date.accessioned2015-01-06T17:16:51Z-
dc.date.available2015-01-06T17:16:51Z-
dc.date.issued2014-
dc.identifier.issn2005-6737-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99680-
dc.description.abstractPURPOSE: This study was conducted to evaluate prognostic factors and cancer-specific survival (CSS) in a cohort of 41 patients with urachal carcinoma by use of a Bayesian model-averaging approach. MATERIALS AND METHODS: Our cohort included 41 patients with urachal carcinoma who underwent extended partial cystectomy, total cystectomy, transurethral resection, chemotherapy, or radiotherapy at a single institute. All patients were classified by both the Sheldon and the Mayo staging systems according to histopathologic reports and preoperative radiologic findings. Kaplan-Meier survival curves and Cox proportional-hazards regression models were carried out to investigate prognostic factors, and a Bayesian model-averaging approach was performed to confirm the significance of each variable by using posterior probabilities. RESULTS: The mean age of the patients was 49.88 ± 13.80 years and the male-to-female ratio was 24:17. The median follow-up was 5.42 years (interquartile range, 2.8-8.4 years). Five- and 10-year CSS rates were 55.9% and 43.4%, respectively. Lower Sheldon (p=0.004) and Mayo (p<0.001) stage, mucinous adenocarcinoma (p=0.005), and larger tumor size (p=0.023) were significant predictors of high survival probability on the basis of a log-rank test. By use of the Bayesian model-averaging approach, higher Mayo stage and larger tumor size were significant predictors of cancer-specific mortality in urachal carcinoma. CONCLUSIONS: The Mayo staging system might be more effective than the Sheldon staging system. In addition, the multivariate analyses suggested that tumor size may be a prognostic factor for urachal carcinoma.-
dc.description.statementOfResponsibilityopen-
dc.format.extent574~580-
dc.relation.isPartOfKOREAN JOURNAL OF UROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBayes Theorem-
dc.subject.MESHCarcinoma/pathology*-
dc.subject.MESHCarcinoma/therapy*-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPrognosis-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRisk Factors-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUrinary Bladder Neoplasms/pathology*-
dc.subject.MESHUrinary Bladder Neoplasms/therapy*-
dc.titlePrognostic Factors for Urachal Cancer: A Bayesian Model-Averaging Approach-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨기과학)-
dc.contributor.googleauthorIn Kyong Kim-
dc.contributor.googleauthorJoo Yong Lee-
dc.contributor.googleauthorJong Kyou Kwon-
dc.contributor.googleauthorJae Joon Park-
dc.contributor.googleauthorKang Su Cho-
dc.contributor.googleauthorWon Sik Ham-
dc.contributor.googleauthorSung Joon Hong-
dc.contributor.googleauthorSeung Choul Yang-
dc.contributor.googleauthorYoung Deuk Choi-
dc.identifier.doi10.4111/kju.2014.55.9.574-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02294-
dc.contributor.localIdA03161-
dc.contributor.localIdA03801-
dc.contributor.localIdA04111-
dc.contributor.localIdA04337-
dc.contributor.localIdA04402-
dc.contributor.localIdA00250-
dc.relation.journalcodeJ02134-
dc.identifier.eissn2005-6745-
dc.identifier.pmid25237458-
dc.subject.keywordFollow-up studies-
dc.subject.keywordSurvival-
dc.subject.keywordUrachal cancer-
dc.contributor.alternativeNameYang, Seung Choul-
dc.contributor.alternativeNameLee, Joo Yong-
dc.contributor.alternativeNameCho, Kang Su-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameHam, Won Sik-
dc.contributor.alternativeNameHong, Sung Joon-
dc.contributor.alternativeNameKwon, Jong Kyou-
dc.contributor.affiliatedAuthorYang, Seung Choul-
dc.contributor.affiliatedAuthorLee, Joo Yong-
dc.contributor.affiliatedAuthorCho, Kang Su-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorHam, Won Sik-
dc.contributor.affiliatedAuthorHong, Sung Joon-
dc.contributor.affiliatedAuthorKwon, Jong Kyou-
dc.citation.volume55-
dc.citation.number9-
dc.citation.startPage574-
dc.citation.endPage580-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF UROLOGY, Vol.55(9) : 574-580, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers

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