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Real-Time Elastography in the Evaluation of Diffuse Thyroid Disease: A Study Based on Elastography Histogram Parameters

Authors
 Jung Hyun Yoon  ;  Jaeheung Yoo  ;  Eun-Kyung Kim  ;  Hee Jung Moon  ;  Hye Sun Lee  ;  Jae Young Seo  ;  Hye Young Park  ;  Woon-Ju Park  ;  Jin Young Kwak 
Citation
 ULTRASOUND IN MEDICINE AND BIOLOGY, Vol.40(9) : 2012-2019, 2014 
Journal Title
 ULTRASOUND IN MEDICINE AND BIOLOGY 
ISSN
 0301-5629 
Issue Date
2014
MeSH
Adult ; Aged ; Computer Systems ; Elasticity Imaging Techniques/methods* ; Female ; Humans ; Male ; Middle Aged ; Principal Component Analysis ; ROC Curve ; Reproducibility of Results ; Sensitivity and Specificity ; Thyroid Diseases/diagnostic imaging* ; Thyroid Gland/diagnostic imaging* ; Young Adult
Keywords
Diffuse thyroid disease ; Real-time elastography ; Thyroid ; Thyroiditis ; Ultrasound
Abstract
The purpose of this study was to evaluate the diagnostic performance of quantitative histogram parameters using real-time tissue elastography (RTE) in the diagnosis of patients with diffuse thyroid disease. One hundred and sixteen patients (mean age, 43.7 ± 10.97 y) who had undergone pre-operative staging ultrasonography and RTE were included. For each patient, 11 parameters were obtained from RTE images, from which the “elastic index” was calculated. Diagnostic performance of the elastic index and that of the 11 parameters on RTE were calculated and compared. Of the 116 patients, 31 had diffuse thyroid disease and 85 had normal thyroid parenchyma. Area under the receiver operating characteristic curve (Az) of MEAN (average relative value) elasticity was high (0.737), without significant differences from other elasticity values. Diagnostic performance of the elastic index was higher than the MEAN, Az = 0.753, without significance (p = 0.802). In conclusion, RTE using the elastic index was found to have good diagnostic performance and may be useful in the diagnosis and management of patients with diffuse thyroid disease.
Full Text
http://www.sciencedirect.com/science/article/pii/S0301562914002191
DOI
10.1016/j.ultrasmedbio.2014.03.033
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Kwak, Jin Young(곽진영) ORCID logo https://orcid.org/0000-0002-6212-1495
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Moon, Hee Jung(문희정) ORCID logo https://orcid.org/0000-0002-5643-5885
Yoon, Jung Hyun(윤정현) ORCID logo https://orcid.org/0000-0002-2100-3513
Lee, Hye Sun(이혜선) ORCID logo https://orcid.org/0000-0001-6328-6948
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99396
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