Cited 6 times in
Association between Apolipoprotein B/Apolipoprotein A-1 and arterial stiffness in metabolic syndrome
DC Field | Value | Language |
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dc.contributor.author | 강신애 | - |
dc.contributor.author | 김경래 | - |
dc.contributor.author | 박종숙 | - |
dc.contributor.author | 백혜리 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 하지윤 | - |
dc.date.accessioned | 2015-01-06T17:02:27Z | - |
dc.date.available | 2015-01-06T17:02:27Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99246 | - |
dc.description.abstract | BACKGROUND: Apolipoprotein B/Apolipoprotein A-1 ratio (Apo B/Apo A-1) is known to be associated with atherosclerotic vascular disease. However, few studies have investigated the relationship between Apo B/Apo A-1 ratio and arterial stiffness, thus we investigated the relationships between Apo B/Apo A-1 and arterial stiffness in patients with metabolic syndrome (MetS). METHODS:1252 subjects with MetS according to the Adult Treatment Panel III were enrolled in our study. Anthropometric profiles and serum concentrations of Apo B, Apo A-1, fasting plasma glucose (FPG), total cholesterol (TC), triglycerides (TG), and high density lipoprotein cholesterol (HDL-C) were measured. Pulse wave velocity (PWV) was evaluated to assess arterial stiffness. RESULTS:The subjects were stratified into four groups according to their Apo B/Apo A-1 ratios. PWV gradually increased according to Apo B/Apo A-1 quartiles. After adjusting for age, arterial stiffness was significantly correlated with systolic blood pressure, diastolic blood pressure, FPG, homeostasis model assessment (HOMA-IR), Apo B and Apo B/Apo A-1. In multiple logistic regression analysis after adjusting for risk factors, Apo B/Apo A-1 ratio was a significant contributor to increased PWV. CONCLUSION:These results suggest that Apo B/Apo A-1 is independently associated with increased arterial stiffness in patients with MetS. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 115~119 | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Apolipoprotein A-I/blood* | - |
dc.subject.MESH | Apolipoproteins B/blood* | - |
dc.subject.MESH | Biomarkers | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Metabolic Syndrome/blood* | - |
dc.subject.MESH | Metabolic Syndrome/diagnosis* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Population Surveillance*/methods | - |
dc.subject.MESH | Vascular Stiffness/physiology* | - |
dc.title | Association between Apolipoprotein B/Apolipoprotein A-1 and arterial stiffness in metabolic syndrome | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Min Kyung Kim | - |
dc.contributor.googleauthor | Chul Woo Ahn | - |
dc.contributor.googleauthor | Shinae Kang | - |
dc.contributor.googleauthor | Ji Yoon Ha | - |
dc.contributor.googleauthor | Haeri Baek | - |
dc.contributor.googleauthor | Jong Suk Park | - |
dc.contributor.googleauthor | Kyung Rae Kim | - |
dc.identifier.doi | 10.1016/j.cca.2014.07.005 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00052 | - |
dc.contributor.localId | A00294 | - |
dc.contributor.localId | A01845 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A04261 | - |
dc.contributor.localId | A01660 | - |
dc.relation.journalcode | J00543 | - |
dc.identifier.eissn | 1873-3492 | - |
dc.identifier.pmid | 25025299 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009898114002927 | - |
dc.subject.keyword | Apolipoprotein A-1 | - |
dc.subject.keyword | Apolipoprotein B | - |
dc.subject.keyword | Apolipoprotein B/Apolipoprotein A-1 ratio | - |
dc.subject.keyword | Arterial stiffness | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.contributor.alternativeName | Kang, Shin Ae | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.alternativeName | Park, Jong Suk | - |
dc.contributor.alternativeName | Baek, Hae Ri | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Ha, Ji Yoon | - |
dc.contributor.affiliatedAuthor | Kang, Shin Ae | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Rae | - |
dc.contributor.affiliatedAuthor | Baek, Hae Ri | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Ha, Ji Yoon | - |
dc.contributor.affiliatedAuthor | Park, Jong Suk | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 473C | - |
dc.citation.startPage | 115 | - |
dc.citation.endPage | 119 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, Vol.473C : 115-119, 2014 | - |
dc.identifier.rimsid | 55961 | - |
dc.type.rims | ART | - |
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