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Evaluation of dry eye and meibomian gland dysfunction after cataract surgery

Authors
 Kyung Eun Han  ;  Sang Chul Yoon  ;  Ji Min Ahn  ;  Sang Min Nam  ;  R. Doyle Stulting  ;  Eung Kweon Kim  ;  Kyoung Yul Seo 
Citation
 AMERICAN JOURNAL OF OPHTHALMOLOGY, Vol.157(6) : 1144-1150, 2014 
Journal Title
 AMERICAN JOURNAL OF OPHTHALMOLOGY 
ISSN
 0002-9394 
Issue Date
2014
MeSH
Aged ; Dry Eye Syndromes/diagnosis* ; Dry Eye Syndromes/etiology ; Dry Eye Syndromes/physiopathology ; Eyelid Diseases/diagnosis* ; Eyelid Diseases/etiology ; Eyelid Diseases/physiopathology ; Female ; Humans ; Lens Implantation, Intraocular ; Male ; Meibomian Glands/pathology* ; Middle Aged ; Phacoemulsification* ; Postoperative Complications* ; Prospective Studies ; Tears/chemistry ; Visual Acuity/physiology
Abstract
PURPOSE: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. DESIGN:Prospective observational case series. METHODS:We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. RESULTS:The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). CONCLUSION:Meibomian gland function may be altered without accompanying structural changes after cataract surgery.
Full Text
http://www.sciencedirect.com/science/article/pii/S0002939414001007
DOI
10.1016/j.ajo.2014.02.036
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Humanities and Social Sciences (인문사회의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Seo, Kyoung Yul(서경률) ORCID logo https://orcid.org/0000-0002-9855-1980
Yoon, Sang Chul(윤상철) ORCID logo https://orcid.org/0000-0003-0454-9597
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99216
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