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Effect of Dexmedetomidine on the Corrected QT and Tp-e Intervals during Spinal Anesthesia

DC Field Value Language
dc.contributor.author김소연-
dc.contributor.author김영순-
dc.contributor.author이종석-
dc.contributor.author한동우-
dc.date.accessioned2015-01-06T16:57:59Z-
dc.date.available2015-01-06T16:57:59Z-
dc.date.issued2014-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99113-
dc.description.abstractPURPOSE: The aim of this study is to evaluate the effect of dexmedetomidine on corrected QT (QTc) and Tp-e intervals in patients undergoing spinal anesthesia. MATERIALS AND METHODS: We studied 50 patients who were scheduled to undergo spinal anesthesia before orthopedic surgeries. Patients were allocated to receive either an infusion of dexmedetomidine or normal saline after spinal anesthesia. RESULTS: QTc intervals were significantly prolonged after spinal anesthesia, and the prolonged QTc interval returned to baseline values 10 minutes after either normal saline or dexmedetomidine administration in both groups. The QTc interval values after dexmedetomidine administration were significantly shorter compared to the QTc interval values just before dexmedetomidine administration. CONCLUSION: Dexmedetomidine could promote the return of a prolonged QTc interval induced by spinal anesthesia and might be helpful in patients who have a prolonged QTc interval.-
dc.description.statementOfResponsibilityopen-
dc.format.extent517~522-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAnesthesia, Spinal/adverse effects*-
dc.subject.MESHBlood Pressure/drug effects-
dc.subject.MESHDexmedetomidine/therapeutic use*-
dc.subject.MESHElectrocardiography-
dc.subject.MESHFemale-
dc.subject.MESHHeart Rate/drug effects-
dc.subject.MESHHumans-
dc.subject.MESHHypnotics and Sedatives/therapeutic use-
dc.subject.MESHLong QT Syndrome/chemically induced-
dc.subject.MESHLong QT Syndrome/drug therapy*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHReference Values-
dc.subject.MESHYoung Adult-
dc.subject.MESHs-
dc.titleEffect of Dexmedetomidine on the Corrected QT and Tp-e Intervals during Spinal Anesthesia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorYoungsoon Kim-
dc.contributor.googleauthorSo Yeon Kim-
dc.contributor.googleauthorJong Seok Lee-
dc.contributor.googleauthorHee Jung Kong-
dc.contributor.googleauthorDong Woo Han-
dc.identifier.doi10.3349/ymj.2014.55.2.517-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00716-
dc.contributor.localIdA04274-
dc.contributor.localIdA00616-
dc.contributor.localIdA03141-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid24532526-
dc.subject.keywordDexmedetomidine-
dc.subject.keywordelectrocardiogram-
dc.subject.keywordspinal anesthesia-
dc.contributor.alternativeNameKim, So Yeon-
dc.contributor.alternativeNameKim, Young Soon-
dc.contributor.alternativeNameLee, Jong Seok-
dc.contributor.alternativeNameHan, Dong Woo-
dc.contributor.affiliatedAuthorKim, Young Soon-
dc.contributor.affiliatedAuthorHan, Dong Woo-
dc.contributor.affiliatedAuthorKim, So Yeon-
dc.contributor.affiliatedAuthorLee, Jong Seok-
dc.citation.volume55-
dc.citation.number2-
dc.citation.startPage517-
dc.citation.endPage522-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.55(2) : 517-522, 2014-
dc.identifier.rimsid50268-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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