Cited 33 times in
The effects of statin use on the development of tuberculosis among patients with diabetes mellitus
DC Field | Value | Language |
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dc.contributor.author | 강영애 | - |
dc.date.accessioned | 2015-01-06T16:50:44Z | - |
dc.date.available | 2015-01-06T16:50:44Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98880 | - |
dc.description.abstract | OBJECTIVE: To evaluate whether statin use affects the development of tuberculosis (TB) among patients with diabetes mellitus (DM). METHODS: This is a retrospective cohort study of patients with newly diagnosed type 2 DM based on the South Korean nationwide claims database. The participants were type 2 DM patients aged 20-99 years who were newly treated with anti-diabetic drugs between 1 January 2007 and 31 December 2010. Patients who had statin prescriptions before a diagnosis of diabetes or were diagnosed with TB before diabetes were excluded. RESULTS: Of 840,899 newly diagnosed type 2 DM patients, 281,842 (33.5%) patients were statin users and 559,057 (66.5%) were non-users. During the study period, 4052 individuals were diagnosed with TB; the estimated incidence of TB in our cohort was 251/100,000 patient-years (95%CI 243-258). In comparison to non-TB patients, statin users were less frequent among TB patients (19.2% vs. 33.6%). After adjustment for potential baseline confounders, statin use was not associated with the development of TB in DM patients (aHR 0.98; 95%CI 0.89-1.07). CONCLUSIONS: TB development among newly diagnosed type 2 DM was considerable, and statin use among these diabetics was not associated with a protective effect on TB incidence. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 717~724 | - |
dc.language | English | - |
dc.publisher | The Union | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/diagnosis | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/drug therapy | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/epidemiology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use* | - |
dc.subject.MESH | Hypoglycemic Agents/therapeutic use | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Protective Factors | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Tuberculosis/diagnosis | - |
dc.subject.MESH | Tuberculosis/epidemiology* | - |
dc.subject.MESH | Young Adult | - |
dc.title | The effects of statin use on the development of tuberculosis among patients with diabetes mellitus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Kang, Y. A. | - |
dc.contributor.googleauthor | Choi, N-K. | - |
dc.contributor.googleauthor | Seong, J-M. | - |
dc.contributor.googleauthor | Heo, E. Y. | - |
dc.contributor.googleauthor | Koo, B. K. | - |
dc.contributor.googleauthor | Hwang, S-S. | - |
dc.contributor.googleauthor | Park, B-J. | - |
dc.contributor.googleauthor | Yim, J-J | - |
dc.contributor.googleauthor | Lee, C-H. | - |
dc.identifier.doi | 10.5588/ijtld.13.0854 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00057 | - |
dc.relation.journalcode | J01167 | - |
dc.identifier.eissn | 1815-7920 | - |
dc.identifier.pmid | 24903944 | - |
dc.identifier.url | http://www.ingentaconnect.com/content/iuatld/ijtld/2014/00000018/00000006/art00017?token=00541c546e12c6422d865c5f3b3b474666767034257b5576427b6c4f582a2f433e402c3568263c2b5d86 | - |
dc.subject.keyword | diabetes mellitus | - |
dc.subject.keyword | statin | - |
dc.subject.keyword | tuberculosis | - |
dc.contributor.alternativeName | Kang, Young Ae | - |
dc.contributor.affiliatedAuthor | Kang, Young Ae | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 18 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 717 | - |
dc.citation.endPage | 724 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol.18(6) : 717-724, 2014 | - |
dc.identifier.rimsid | 38842 | - |
dc.type.rims | ART | - |
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