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Solitary lateral neck node metastasis in papillary thyroid carcinoma

DC Field Value Language
dc.contributor.author김법우-
dc.contributor.author김석모-
dc.contributor.author박정수-
dc.contributor.author이용상-
dc.contributor.author장항석-
dc.contributor.author장호진-
dc.contributor.author전기원-
dc.date.accessioned2015-01-06T16:45:56Z-
dc.date.available2015-01-06T16:45:56Z-
dc.date.issued2014-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98725-
dc.description.abstractBACKGROUND: Papillary thyroid carcinoma (PTC) is associated with a high incidence of regional node metastasis, but the patterns of lateral neck node metastasis (LNM) vary. Occasionally, a solitary LNM (SLNM) is seen in PTC patients. We therefore assessed whether selective single level node dissection is appropriate in PTC patients with SLNM. METHODS: We retrospectively reviewed the medical records of 241 PTC patients who underwent total thyroidectomy with central neck dissection plus ipsilateral internal jugular node dissection (level II to IV) between January 2010 and December 2011. Of these patients, 51 had SLNM and 190 had multiple LNM (MLNM). The clinicopathologic characteristics of the two groups were compared. RESULTS: Age, gender ratio, and numbers of lateral neck nodes harvested (29.4±11.0 versus 30.3±9.5; P=0.574) were similar in the SLNM and MLNM groups. Mean primary tumor size was significantly smaller in the SLNM than in the MNLM group (1.03 cm versus 1.35 cm; P=0.037). The proportion of patients with primary tumor≤1 cm was significantly greater in the SLNM group (60.8% versus 38.4%; P=0.006), whereas the proportion with maximal node size≤0.7 cm (28.9% versus 73.3%; P<0.001) and the proportion with capsular invasion (62.7% versus 83.7%, P=0.002) were significantly lower in the SLNM than in the MLNM group. CONCLUSIONS: Selective single level neck dissection can be considered as an alternative to systemic lateral neck dissection in PTC patients with SLNM, maximal metastatic node size≤0.7 cm, and no extrathyroidal invasion.-
dc.description.statementOfResponsibilityopen-
dc.format.extent109-
dc.relation.isPartOfWORLD JOURNAL OF SURGICAL ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHBone Morphogenetic Protein 2/genetics-
dc.subject.MESHBone Morphogenetic Protein 2/pharmacology-
dc.subject.MESHBone Morphogenetic Protein Receptors, Type I/genetics*-
dc.subject.MESHEpithelium/metabolism-
dc.subject.MESHGene Expression Regulation/genetics*-
dc.subject.MESHGenetic Vectors/genetics-
dc.subject.MESHLentivirus/genetics-
dc.subject.MESHMale-
dc.subject.MESHMesoderm/metabolism-
dc.subject.MESHMice-
dc.subject.MESHMice, Nude-
dc.subject.MESHMicroRNAs/antagonists & inhibitors-
dc.subject.MESHMicroRNAs/genetics*-
dc.subject.MESHOdontogenesis/genetics*-
dc.subject.MESHRecombinant Proteins/pharmacology-
dc.subject.MESHSignal Transduction/genetics*-
dc.subject.MESHTooth Germ/drug effects-
dc.subject.MESHTooth Germ/metabolism-
dc.subject.MESHTooth Germ/transplantation-
dc.subject.MESHTranscription, Genetic/genetics-
dc.subject.MESHTransforming Growth Factor beta/Adolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCarcinoma, Papillary/secondary*-
dc.subject.MESHCarcinoma, Papillary/surgery-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHLymph Nodes/pathology*-
dc.subject.MESHLymph Nodes/surgery-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeck Dissection/methods*-
dc.subject.MESHNeoplasm Invasiveness-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPrognosis-
dc.subject.MESHROC Curve-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHThyroid Neoplasms/pathology*-
dc.subject.MESHThyroid Neoplasms/surgery-
dc.subject.MESHThyroidectomy*-
dc.subject.MESHYoung Adultmacology-
dc.subject.MESHSubstances-
dc.titleSolitary lateral neck node metastasis in papillary thyroid carcinoma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorSeok-Mo Kim-
dc.contributor.googleauthorKi Won Chun-
dc.contributor.googleauthorHo Jin Chang-
dc.contributor.googleauthorBup-Woo Kim-
dc.contributor.googleauthorYong Sang Lee-
dc.contributor.googleauthorHang-Seok Chang-
dc.contributor.googleauthorCheong Soo Park-
dc.identifier.doi10.1186/1477-7819-12-109-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01646-
dc.contributor.localIdA00491-
dc.contributor.localIdA00542-
dc.contributor.localIdA02978-
dc.contributor.localIdA03488-
dc.contributor.localIdA03496-
dc.contributor.localIdA03504-
dc.relation.journalcodeJ02803-
dc.identifier.eissn1477-7819-
dc.identifier.pmid24755464-
dc.subject.keywordthyroid-
dc.subject.keywordpapillary-
dc.subject.keywordsolitary-
dc.subject.keywordmetastasis-
dc.contributor.alternativeNameKim, Bup Woo-
dc.contributor.alternativeNameKim, Seok Mo-
dc.contributor.alternativeNamePark, Cheong Soo-
dc.contributor.alternativeNameLee, Yong Sang-
dc.contributor.alternativeNameChang, Hang Seok-
dc.contributor.alternativeNameChang, Ho Jin-
dc.contributor.alternativeNameChun, Ki Won-
dc.contributor.affiliatedAuthorPark, Cheong Soo-
dc.contributor.affiliatedAuthorKim, Bup Woo-
dc.contributor.affiliatedAuthorKim, Seok Mo-
dc.contributor.affiliatedAuthorLee, Yong Sang-
dc.contributor.affiliatedAuthorChang, Hang Seok-
dc.contributor.affiliatedAuthorChang, Ho Jin-
dc.contributor.affiliatedAuthorChun, Ki Won-
dc.citation.volume12-
dc.citation.number1-
dc.citation.startPage109-
dc.identifier.bibliographicCitationWORLD JOURNAL OF SURGICAL ONCOLOGY, Vol.12(1) : 109, 2014-
dc.identifier.rimsid38565-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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