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Prevalence of Sexually Transmitted Infections in Korean Healthy Women; Implications of Multiplex PCR pathogen detection on antibiotic therapy

DC FieldValueLanguage
dc.contributor.author김윤정-
dc.contributor.author이경아-
dc.date.accessioned2015-01-06T16:44:11Z-
dc.date.available2015-01-06T16:44:11Z-
dc.date.issued2014-
dc.identifier.issn1341-321X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98667-
dc.description.abstractIn this study, we investigated the prevalence of sexually transmitted infections (STIs) using multiplex real-time PCR assay in healthy Korean women. We also evaluated the risk factors of STIs, and compared the various factors between the STI-positive and the STI-negative groups. A total of 799 endocervical swab samples from healthy Korean women who visited our hospital for general medical check-ups during January 2012 to October 2012 were included. Eight STIs including Human papillomavirus (HPV), Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Mycoplasma genitalium (MG), Mycoplasma hominis (MH), Ureaplasma urealyticum (UU), Ureaplasma parvum (UP), and Trichomonas vaginalis (TV) were detected using Anyplex II STI-7 Detection assay Detection (Seegene, Seoul, Korea) and Hybrid Capture 2 High-Risk HPV DNA test (Digene Corporation, Gaithersburg, MD, USA) according manufacture's protocols. Ninety-seven (12.1%) subjects were positive for HPV. Of 393 (49.2%) subjects were infected with at least one microorganism and a total of 499 STIs were identified. Among the 393 STI-positive subjects, the proportion of single, double and triple infection was 76.3%, 20.4% and 3.3%, respectively. The median age of the STI-positive group (47 years, range 42-52) was younger than the STI-negative group (49 years, range 43-56; P < 0.001). The infection rate of HPV was significantly higher in the STI-positive group (15.8%, 62/393) than the STI-negative group (8.6%, 35/406) (P = 0.002).-
dc.description.statementOfResponsibilityopen-
dc.format.extent74~76-
dc.relation.isPartOfJOURNAL OF INFECTION AND CHEMOTHERAPY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAnti-Bacterial Agents/therapeutic use*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultiplex Polymerase Chain Reaction/methods-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHSexually Transmitted Diseases, Bacterial/drug therapy*-
dc.subject.MESHSexually Transmitted Diseases, Bacterial/epidemiology*-
dc.subject.MESHSexually Transmitted Diseases, Bacterial/microbiology-
dc.subject.MESHSexually Transmitted Diseases, Viral/drug therapy*-
dc.subject.MESHSexually Transmitted Diseases, Viral/epidemiology*-
dc.subject.MESHSexually Transmitted Diseases, Viral/virology-
dc.titlePrevalence of Sexually Transmitted Infections in Korean Healthy Women; Implications of Multiplex PCR pathogen detection on antibiotic therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorYoonjung Kim-
dc.contributor.googleauthorJuwon Kim-
dc.contributor.googleauthorKyung-A Lee-
dc.identifier.doi10.1016/j.jiac.2013.08.005-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00793-
dc.contributor.localIdA02647-
dc.relation.journalcodeJ01453-
dc.identifier.eissn1437-7780-
dc.identifier.pmid24462432-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1341321X13000305-
dc.subject.keywordHuman papillomavirus-
dc.subject.keywordPolymerase chain reaction-
dc.subject.keywordSexually transmitted infections-
dc.contributor.alternativeNameKim, Yoon Jung-
dc.contributor.alternativeNameLee, Kyung A-
dc.contributor.affiliatedAuthorKim, Yoon Jung-
dc.contributor.affiliatedAuthorLee, Kyung A-
dc.rights.accessRightsfree-
dc.citation.volume20-
dc.citation.number1-
dc.citation.startPage74-
dc.citation.endPage76-
dc.identifier.bibliographicCitationJOURNAL OF INFECTION AND CHEMOTHERAPY, Vol.20(1) : 74-76, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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