Cited 50 times in
Interdialytic Weight Gain and Cardiovascular Outcome in Incident Hemodialysis Patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김찬호 | - |
dc.contributor.author | 도화미 | - |
dc.contributor.author | 박정탁 | - |
dc.contributor.author | 오형중 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 이미정 | - |
dc.contributor.author | 한승혁 | - |
dc.contributor.author | 강신욱 | - |
dc.contributor.author | 구향모 | - |
dc.date.accessioned | 2015-01-06T16:43:51Z | - |
dc.date.available | 2015-01-06T16:43:51Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0250-8095 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98656 | - |
dc.description.abstract | BACKGROUND: Interdialytic weight gain (IDWG) has been regarded as a surrogate of volume overload, but also as a marker of a better nutritional status in end-stage renal disease (ESRD) patients on hemodialysis (HD). This paradoxical meaning of IDWG requires further investigation, particularly in adverse cardiovascular outcomes. METHODS: A prospective cohort of 1,013 incident HD patients from 36 HD centers of the Clinical Research Center for ESRD in Korea was included. Patients were categorized into five groups according to the IDWG%, a ratio of absolute IDWG to dry weight: <1.0, ≥4.0, and every 1.0 increment in between. Primary outcome was major adverse cardiac and cerebrovascular events (MACCE). RESULTS: During a mean follow-up of 18.7 months, primary outcome was observed in 104 patients (10.3%). In multivariate analysis, compared to patients with IDWG% of 1.0-1.9 (reference group), the hazard ratios (HRs) for primary outcome in the IDWG% <1.0, 2.0-2.9, 3.0-3.9, and ≥4.0 groups were 1.10 [95% confidence interval (CI) 0.55-2.20, p = 0.80], 1.15 (95% CI 0.59-2.27, p = 0.68), 1.80 (95% CI 0.95-3.41, p = 0.07), and 1.93 (95% CI 1.02-3.64, p = 0.04), respectively. Furthermore, even when residual renal function and 24-hour urine volume were adjusted, IDWG% ≥4.0 remained as a significant predictor of primary outcome (HR 2.03, 95% CI 1.02-4.02, p = 0.04). CONCLUSION: Increased IDWG% is a significant independent predictor of MACCE in incident HD patients. It could be helpful to prevent excessive IDWG for improving clinical outcomes in incident HD patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 427~435 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF NEPHROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Angina, Unstable/mortality | - |
dc.subject.MESH | Cardiovascular Diseases/mortality* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Failure/mortality | - |
dc.subject.MESH | Hospitalization | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Failure, Chronic/therapy* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Myocardial Infarction/mortality | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Renal Dialysis* | - |
dc.subject.MESH | Stroke/mortality | - |
dc.subject.MESH | Weight Gain* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Interdialytic Weight Gain and Cardiovascular Outcome in Incident Hemodialysis Patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Lee M.J. | - |
dc.contributor.googleauthor | Doh F.M. | - |
dc.contributor.googleauthor | Kim C.H. | - |
dc.contributor.googleauthor | Koo H.M. | - |
dc.contributor.googleauthor | Oh H.J. | - |
dc.contributor.googleauthor | Park J.T. | - |
dc.contributor.googleauthor | Han S.H. | - |
dc.contributor.googleauthor | Yoo T.-H. | - |
dc.contributor.googleauthor | Kim Y.-L. | - |
dc.contributor.googleauthor | Kim Y.S. | - |
dc.contributor.googleauthor | Yang C.W. | - |
dc.contributor.googleauthor | Kim N.-H. | - |
dc.contributor.googleauthor | Kang S.-W. | - |
dc.identifier.doi | 10.1159/000362743 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01037 | - |
dc.contributor.localId | A01315 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02417 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A04304 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A00203 | - |
dc.contributor.localId | A02773 | - |
dc.relation.journalcode | J00094 | - |
dc.identifier.eissn | 1421-9670 | - |
dc.identifier.pmid | 24819227 | - |
dc.subject.keyword | Cardiovascular outcome | - |
dc.subject.keyword | Hemodialysis | - |
dc.subject.keyword | Interdialytic weight gain | - |
dc.contributor.alternativeName | Kim, Chan Ho | - |
dc.contributor.alternativeName | Doh, Fa Mee | - |
dc.contributor.alternativeName | Park, Jung Tak | - |
dc.contributor.alternativeName | Oh, Hyung Jung | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.alternativeName | Lee, Mi Jung | - |
dc.contributor.alternativeName | Han, Seung Hyeok | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.alternativeName | Koo, Hyang Mo | - |
dc.contributor.affiliatedAuthor | Kim, Chan Ho | - |
dc.contributor.affiliatedAuthor | Doh, Fa Mee | - |
dc.contributor.affiliatedAuthor | Park, Jung Tak | - |
dc.contributor.affiliatedAuthor | Oh, Hyung Jung | - |
dc.contributor.affiliatedAuthor | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Han, Seung Hyeok | - |
dc.contributor.affiliatedAuthor | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Koo, Hyang Mo | - |
dc.contributor.affiliatedAuthor | Lee, Mi Jung | - |
dc.citation.volume | 39 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 427 | - |
dc.citation.endPage | 435 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF NEPHROLOGY, Vol.39(5) : 427-435, 2014 | - |
dc.identifier.rimsid | 38177 | - |
dc.type.rims | ART | - |
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