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For Patients with Primary Achalasia the Clinical Success of Pneumatic Balloon Dilatation Can Be Predicted from the Residual Fraction of Radionuclide During Esophageal Transit Scintigraphy

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dc.contributor.author윤영훈-
dc.contributor.author이광원-
dc.contributor.author전한호-
dc.contributor.author김지현-
dc.contributor.author박효진-
dc.date.accessioned2015-01-06T16:40:01Z-
dc.date.available2015-01-06T16:40:01Z-
dc.date.issued2014-
dc.identifier.issn0163-2116-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98532-
dc.description.abstractBACKGROUND: Esophageal transit scintigraphy (ETS) and esophagography have long been used to evaluate patients with achalasia. The objectives of our study were to evaluate the efficacy of endoscopic pneumatic dilatation (EPD) as treatment for Koreans with achalasia and to determine which findings from ETS and esophagography predict successful treatment of achalasia. METHODS: Patients with achalasia who were treated by EPD between April 2002 and January 2012 were recruited. We defined the success of EPD as 6 months or more of clinical remission without symptoms or a decrease in the Eckardt scores by at least two points and a total Eckardt score not exceeding 3. We reviewed the percentage of maximum scintigraphic activity retained in the esophagus at 30 s (R 30) and the post-PD rate of reduction of R 30 ((Pre R 30 - Post R 30)/Pre R 30 × 100) by ETS. Possible predictive factors determined by ETS and esophagography were analyzed. RESULTS: Our study included 53 eligible patients. The median symptom score (Eckardt score) was 5 (4-8). R 30 and T 1/2 were, respectively, 61.8 % and 38.5 min before EPD and 20 % and 4.19 min after EPD. Successful EPD was achieved for 40 of 53 (75.47 %) patients. Age (≥40, p = 0.027) and post-PD rate of reduction of R 30 (>20 %, p = 0.003) were best prognostic indicators of clinical success. There were no perforations related to EPD. CONCLUSION: Older age and a post-PD rate of reduction of R 30 were strongly associated with better outcomes. Examination with ETS before and after EPD can be used to objectively assess a patient's short-term response to EPD.-
dc.description.statementOfResponsibilityopen-
dc.format.extent375~382-
dc.relation.isPartOfDIGESTIVE DISEASES AND SCIENCES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHAsian Continental Ancestry Group-
dc.subject.MESHDilatation-
dc.subject.MESHEsophageal Achalasia/diagnostic imaging-
dc.subject.MESHEsophageal Achalasia/epidemiology-
dc.subject.MESHEsophageal Achalasia/physiopathology-
dc.subject.MESHEsophageal Achalasia/therapy*-
dc.subject.MESHEsophagoscopy/instrumentation-
dc.subject.MESHEsophagoscopy/methods*-
dc.subject.MESHEsophagus/diagnostic imaging*-
dc.subject.MESHEsophagus/physiopathology-
dc.subject.MESHFemale-
dc.subject.MESHGastrointestinal Motility*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPatient Selection-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHRadiography-
dc.subject.MESHRadionuclide Imaging-
dc.subject.MESHRemission Induction-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titleFor Patients with Primary Achalasia the Clinical Success of Pneumatic Balloon Dilatation Can Be Predicted from the Residual Fraction of Radionuclide During Esophageal Transit Scintigraphy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHan Ho Jeon-
dc.contributor.googleauthorYoung Hoon Youn-
dc.contributor.googleauthorKwangwon Rhee-
dc.contributor.googleauthorJie-Hyun Kim-
dc.contributor.googleauthorHyojin Park-
dc.contributor.googleauthorJeffrey L. Conklin-
dc.identifier.doi10.1007/s10620-013-2906-4-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02583-
dc.contributor.localIdA02671-
dc.contributor.localIdA03559-
dc.contributor.localIdA01774-
dc.contributor.localIdA00996-
dc.relation.journalcodeJ00737-
dc.identifier.eissn1573-2568-
dc.identifier.pmid24166664-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs10620-013-2906-4-
dc.subject.keywordAchalasia-
dc.subject.keywordPrognosis-
dc.subject.keywordPneumatic dilatation-
dc.subject.keywordEsophagography-
dc.subject.keywordEsophageal transit scintigraphy-
dc.contributor.alternativeNameYoun, Young Hoon-
dc.contributor.alternativeNameRhee, Kwang Won-
dc.contributor.alternativeNameJeon, Han Ho-
dc.contributor.alternativeNameKim, Ji Hyun-
dc.contributor.alternativeNamePark, Hyo Jin-
dc.contributor.affiliatedAuthorYoun, Young Hoon-
dc.contributor.affiliatedAuthorRhee, Kwang Won-
dc.contributor.affiliatedAuthorJeon, Han Ho-
dc.contributor.affiliatedAuthorPark, Hyo Jin-
dc.contributor.affiliatedAuthorKim, Ji Hyun-
dc.rights.accessRightsfree-
dc.citation.volume59-
dc.citation.number2-
dc.citation.startPage375-
dc.citation.endPage382-
dc.identifier.bibliographicCitationDIGESTIVE DISEASES AND SCIENCES, Vol.59(2) : 375-382, 2014-
dc.identifier.rimsid57653-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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