Cited 9 times in
For Patients with Primary Achalasia the Clinical Success of Pneumatic Balloon Dilatation Can Be Predicted from the Residual Fraction of Radionuclide During Esophageal Transit Scintigraphy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤영훈 | - |
dc.contributor.author | 이광원 | - |
dc.contributor.author | 전한호 | - |
dc.contributor.author | 김지현 | - |
dc.contributor.author | 박효진 | - |
dc.date.accessioned | 2015-01-06T16:40:01Z | - |
dc.date.available | 2015-01-06T16:40:01Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0163-2116 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98532 | - |
dc.description.abstract | BACKGROUND: Esophageal transit scintigraphy (ETS) and esophagography have long been used to evaluate patients with achalasia. The objectives of our study were to evaluate the efficacy of endoscopic pneumatic dilatation (EPD) as treatment for Koreans with achalasia and to determine which findings from ETS and esophagography predict successful treatment of achalasia. METHODS: Patients with achalasia who were treated by EPD between April 2002 and January 2012 were recruited. We defined the success of EPD as 6 months or more of clinical remission without symptoms or a decrease in the Eckardt scores by at least two points and a total Eckardt score not exceeding 3. We reviewed the percentage of maximum scintigraphic activity retained in the esophagus at 30 s (R 30) and the post-PD rate of reduction of R 30 ((Pre R 30 - Post R 30)/Pre R 30 × 100) by ETS. Possible predictive factors determined by ETS and esophagography were analyzed. RESULTS: Our study included 53 eligible patients. The median symptom score (Eckardt score) was 5 (4-8). R 30 and T 1/2 were, respectively, 61.8 % and 38.5 min before EPD and 20 % and 4.19 min after EPD. Successful EPD was achieved for 40 of 53 (75.47 %) patients. Age (≥40, p = 0.027) and post-PD rate of reduction of R 30 (>20 %, p = 0.003) were best prognostic indicators of clinical success. There were no perforations related to EPD. CONCLUSION: Older age and a post-PD rate of reduction of R 30 were strongly associated with better outcomes. Examination with ETS before and after EPD can be used to objectively assess a patient's short-term response to EPD. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 375~382 | - |
dc.relation.isPartOf | DIGESTIVE DISEASES AND SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Dilatation | - |
dc.subject.MESH | Esophageal Achalasia/diagnostic imaging | - |
dc.subject.MESH | Esophageal Achalasia/epidemiology | - |
dc.subject.MESH | Esophageal Achalasia/physiopathology | - |
dc.subject.MESH | Esophageal Achalasia/therapy* | - |
dc.subject.MESH | Esophagoscopy/instrumentation | - |
dc.subject.MESH | Esophagoscopy/methods* | - |
dc.subject.MESH | Esophagus/diagnostic imaging* | - |
dc.subject.MESH | Esophagus/physiopathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gastrointestinal Motility* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Patient Selection | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Radiography | - |
dc.subject.MESH | Radionuclide Imaging | - |
dc.subject.MESH | Remission Induction | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | For Patients with Primary Achalasia the Clinical Success of Pneumatic Balloon Dilatation Can Be Predicted from the Residual Fraction of Radionuclide During Esophageal Transit Scintigraphy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Han Ho Jeon | - |
dc.contributor.googleauthor | Young Hoon Youn | - |
dc.contributor.googleauthor | Kwangwon Rhee | - |
dc.contributor.googleauthor | Jie-Hyun Kim | - |
dc.contributor.googleauthor | Hyojin Park | - |
dc.contributor.googleauthor | Jeffrey L. Conklin | - |
dc.identifier.doi | 10.1007/s10620-013-2906-4 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02583 | - |
dc.contributor.localId | A02671 | - |
dc.contributor.localId | A03559 | - |
dc.contributor.localId | A01774 | - |
dc.contributor.localId | A00996 | - |
dc.relation.journalcode | J00737 | - |
dc.identifier.eissn | 1573-2568 | - |
dc.identifier.pmid | 24166664 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10620-013-2906-4 | - |
dc.subject.keyword | Achalasia | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Pneumatic dilatation | - |
dc.subject.keyword | Esophagography | - |
dc.subject.keyword | Esophageal transit scintigraphy | - |
dc.contributor.alternativeName | Youn, Young Hoon | - |
dc.contributor.alternativeName | Rhee, Kwang Won | - |
dc.contributor.alternativeName | Jeon, Han Ho | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.alternativeName | Park, Hyo Jin | - |
dc.contributor.affiliatedAuthor | Youn, Young Hoon | - |
dc.contributor.affiliatedAuthor | Rhee, Kwang Won | - |
dc.contributor.affiliatedAuthor | Jeon, Han Ho | - |
dc.contributor.affiliatedAuthor | Park, Hyo Jin | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 59 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 375 | - |
dc.citation.endPage | 382 | - |
dc.identifier.bibliographicCitation | DIGESTIVE DISEASES AND SCIENCES, Vol.59(2) : 375-382, 2014 | - |
dc.identifier.rimsid | 57653 | - |
dc.type.rims | ART | - |
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