Cited 24 times in
First-degree atrioventricular block is associated with advanced atrioventricular block, atrial fibrillation, and left ventricular dysfunction in patients with hypertension
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이문형 | - |
dc.contributor.author | 정보영 | - |
dc.contributor.author | 문희선 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 박준범 | - |
dc.contributor.author | 박희남 | - |
dc.contributor.author | 심재민 | - |
dc.contributor.author | 엄재선 | - |
dc.contributor.author | 위진 | - |
dc.date.accessioned | 2015-01-06T16:39:29Z | - |
dc.date.available | 2015-01-06T16:39:29Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0263-6352 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98515 | - |
dc.description.abstract | OBJECTIVES: Clinical significance of first-degree atrioventricular block (AVB) have not been known in patients with hypertension. This study was performed to elucidate long-term prognosis of first-degree AVB in patients with hypertension. METHODS: We included 3816 patients (mean age, 61.0 ± 10.6 years; men, 47.2%) with hypertension. We reviewed their ECGs and measured the PR interval. The patients were divided into two groups: normal PR interval (120 ms ≤ PR ≤200 ms) and first-degree AVB (PR >200 ms). We compared the incidence, cumulative incidence and hazard ratios of advanced AVB, sick sinus syndrome, atrial fibrillation and left ventricular dysfunction between the two groups during the follow-up period. RESULTS: The prevalence of first-degree AVB in patients with hypertension was 14.3%. The patients were followed up for 9.4 ± 2.4 years. Incidence and cumulative incidence of advanced AVB, atrial fibrillation and left ventricular dysfunction in patients with first-degree AVB were significantly higher than in patients with normal PR interval. By multivariate Cox's regression, patients with first-degree AVB had an increased risk of advanced AVB [hazard ratio 2.77; 95% confidence interval (95% CI) 1.38-5.59; P = 0.004], atrial fibrillation (hazard ratio 2.33; 95% CI 1.84-2.94; P < 0.001) and left ventricular dysfunction (hazard ratio 1.49; 95% CI 1.11-2.00; P = 0.009). However, sick sinus syndrome was not associated with first-degree AVB. CONCLUSION: First-degree AVB is an independent risk factor for future development of advanced AVB, atrial fibrillation and left ventricular dysfunction in patients with hypertension. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1115~1120 | - |
dc.relation.isPartOf | JOURNAL OF HYPERTENSION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Atrial Fibrillation/complications* | - |
dc.subject.MESH | Atrioventricular Block* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension/complications* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Ventricular Dysfunction, Left/complications* | - |
dc.title | First-degree atrioventricular block is associated with advanced atrioventricular block, atrial fibrillation, and left ventricular dysfunction in patients with hypertension | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jae-Sun Uhm | - |
dc.contributor.googleauthor | Jaemin Shim | - |
dc.contributor.googleauthor | Jin Wi | - |
dc.contributor.googleauthor | Hee-Sun Mun | - |
dc.contributor.googleauthor | Junbeom Park | - |
dc.contributor.googleauthor | Sung-Ha Park | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.contributor.googleauthor | Hui-Nam Pak | - |
dc.contributor.googleauthor | Moon-Hyoung Lee | - |
dc.identifier.doi | 10.1097/HJH.0000000000000113 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02766 | - |
dc.contributor.localId | A03609 | - |
dc.contributor.localId | A01396 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A01670 | - |
dc.contributor.localId | A01776 | - |
dc.contributor.localId | A02206 | - |
dc.contributor.localId | A02337 | - |
dc.contributor.localId | A02450 | - |
dc.relation.journalcode | J01448 | - |
dc.identifier.eissn | 1473-5598 | - |
dc.identifier.pmid | 24695396 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004872-201405000-00026&LSLINK=80&D=ovft | - |
dc.subject.keyword | atrial fibrillation | - |
dc.subject.keyword | atrioventricular block | - |
dc.subject.keyword | left ventricular dysfunction | - |
dc.subject.keyword | PR interval | - |
dc.contributor.alternativeName | Lee, Moon Hyoung | - |
dc.contributor.alternativeName | Joung, Bo Young | - |
dc.contributor.alternativeName | Mun, Hee Sun | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Park, Jun Beom | - |
dc.contributor.alternativeName | Pak, Hui Nam | - |
dc.contributor.alternativeName | Shim, Jae Min | - |
dc.contributor.alternativeName | Uhm, Jae Sun | - |
dc.contributor.alternativeName | Wi, Jin | - |
dc.contributor.affiliatedAuthor | Lee, Moon Hyoung | - |
dc.contributor.affiliatedAuthor | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | Mun, Hee Sun | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Park, Jun Beom | - |
dc.contributor.affiliatedAuthor | Pak, Hui Nam | - |
dc.contributor.affiliatedAuthor | Shim, Jae Min | - |
dc.contributor.affiliatedAuthor | Uhm, Jae Sun | - |
dc.contributor.affiliatedAuthor | Wi, Jin | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 32 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1115 | - |
dc.citation.endPage | 1120 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HYPERTENSION, Vol.32(5) : 1115-1120, 2014 | - |
dc.identifier.rimsid | 57641 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.