Cited 3 times in
The effect of insulin resistance on postprandial triglycerides in Korean type 2 diabetic patients
DC Field | Value | Language |
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dc.contributor.author | 강은석 | - |
dc.contributor.author | 이병완 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | 김광준 | - |
dc.date.accessioned | 2015-01-06T16:30:40Z | - |
dc.date.available | 2015-01-06T16:30:40Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0940-5429 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98242 | - |
dc.description.abstract | We hypothesized that the influence of metabolic parameters depends on metabolic syndrome (MetS) status. The clinical and metabolic implications of postprandial triglyceride (ppTG) in Korean type 2 diabetes were investigated in the presence or absence of MetS, MetS+, or MetS−. To investigate the relationship between ppTG and metabolic parameters, we analyzed plasma TG levels in 126 newly diagnosed, drug-naïve diabetic patients after ingestion of a standardized low calorie and fat (500 kcal, 17.5 g fat) liquid meal formula. We report that MetS+ patients have significantly higher BMI, waist/hip ratio, HOMA-IR, and HOMA-β, but insignificantly higher fasting TG, ppTG, and ΔTG than MetS− patients. In the MetS+ patients, ppTG correlated with fasting TG and non-HDL, but was not related to HOMA-IR. In MetS− patients, ppTG correlated with fasting TG, non-HDL, blood pressure, waist/hip ratio, fasting C-peptide and insulin levels, and HOMA-IR. Multivariate analysis showed HOMA-IR to be a predictive factor for ppTG in MetS− patients but not in MetS+ patients. ppTG correlated with IR in MetS− type 2 diabetic patients but not in MetS+. This unexpected result implies that MetS+ diabetic patients already have high fasting TG and that IR influences fasting TG more dominantly than ppTG. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 15~22 | - |
dc.relation.isPartOf | ACTA DIABETOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/blood* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/epidemiology | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Insulin Resistance* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Postprandial Period* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Triglycerides/blood* | - |
dc.title | The effect of insulin resistance on postprandial triglycerides in Korean type 2 diabetic patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Kyeong Hye Park | - |
dc.contributor.googleauthor | Kwang Joon Kim | - |
dc.contributor.googleauthor | Byung-Wan Lee | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.identifier.doi | 10.1007/s00592-012-0420-3 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A02796 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A00317 | - |
dc.relation.journalcode | J00013 | - |
dc.identifier.eissn | 1432-5233 | - |
dc.identifier.pmid | 22854916 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00592-012-0420-3 | - |
dc.subject.keyword | Postprandial triglyceride | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Diabetes mellitus | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Joon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 51 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 15 | - |
dc.citation.endPage | 22 | - |
dc.identifier.bibliographicCitation | ACTA DIABETOLOGICA, Vol.51(1) : 15-22, 2014 | - |
dc.identifier.rimsid | 50742 | - |
dc.type.rims | ART | - |
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