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Cited 18 times in

Serum Cholesterol Concentration and Prevalence, Awareness, Treatment, and Control of High Low‐Density Lipoprotein Cholesterol in the Korea National Health and Nutrition Examination Surveys 2008–2010: Beyond the Tip of the Iceberg

DC FieldValueLanguage
dc.contributor.author이상국-
dc.contributor.author이용호-
dc.contributor.author이현철-
dc.contributor.author차봉수-
dc.contributor.author강은석-
dc.contributor.author김정호-
dc.contributor.author이명하-
dc.contributor.author이병완-
dc.date.accessioned2015-01-06T16:29:32Z-
dc.date.available2015-01-06T16:29:32Z-
dc.date.issued2014-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98206-
dc.description.abstractBACKGROUND: The mortality rate from cardiovascular disease (CVD) among young adults has declined less than that in the older population, raising concerns about the increasing prevalence of obesity-related conditions including hypercholesterolemia in the younger population. We investigated the age-standardized mean levels of serum cholesterols and the prevalence, awareness, treatment and control rates of hyper-low-density lipoprotein (LDL)-cholesterolemia based on age. METHODS AND RESULTS: Nationally representative samples of 19 489 subjects aged ≥20 years were analyzed from the Korea National Health and Nutrition Examination Surveys 2008-2010. Hyper-LDL-cholesterolemia was individually evaluated by the 2004 National Cholesterol Education Program Adult Treatment Panel III guidelines. Age-standardized mean levels of total cholesterol, high-density lipoprotein-cholesterol, LDL-cholesterol, and triglycerides were 186.8, 48.0, 112.9, and 136.0 mg/dL, respectively. Age-standardized prevalence of hyper-LDL-cholesterolemia was 23.2% (men, 25.5%; women, 21.8%). Among subjects with hyper-LDL-cholesterolemia, awareness and treatment rates were significantly lower in younger adults (<50 years) compared to older adults ≥50 years (awareness, 8.0% versus 21.5%; treatment, 5.1% versus 18.5%, all Ps<0.001), indicating significant discrepancies in awareness and treatment rates of hypercholesterolemia between younger and older adults. Among subjects aware of their hyper-LDL-cholesterolemia, younger adults were more likely to have controlled LDL-cholesterol than the elderly (82.1% versus 67.5%, P<0.001). CONCLUSIONS: Compared to the elderly, significant proportions of young and middle-aged adults are unaware of their hypercholesterolemia and are not treated with proper lipid-lowering medications. Early screening, education, and proper management should be stressed in national public healthcare policies to reduce the increasing burden of CVD in the younger population with undiagnosed hypercholesterolemia.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfJOURNAL OF THE AMERICAN HEART ASSOCIATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAge Distribution-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHAnticholesteremic Agents/therapeutic use*-
dc.subject.MESHAwareness*-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHCholesterol, LDL/blood*-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHHealth Behavior-
dc.subject.MESHHealth Knowledge, Attitudes, Practice*-
dc.subject.MESHHealth Surveys-
dc.subject.MESHHumans-
dc.subject.MESHHypercholesterolemia*/blood-
dc.subject.MESHHypercholesterolemia*/diagnosis-
dc.subject.MESHHypercholesterolemia*/drug therapy-
dc.subject.MESHHypercholesterolemia*/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNutrition Surveys-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Factors-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHTriglycerides/blood-
dc.subject.MESHYoung Adult-
dc.titleSerum Cholesterol Concentration and Prevalence, Awareness, Treatment, and Control of High Low‐Density Lipoprotein Cholesterol in the Korea National Health and Nutrition Examination Surveys 2008–2010: Beyond the Tip of the Iceberg-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorYong‐ho Lee-
dc.contributor.googleauthorSang‐Guk Lee-
dc.contributor.googleauthorMyung Ha Lee-
dc.contributor.googleauthorJeong‐Ho Kim-
dc.contributor.googleauthorByung‐Wan Lee-
dc.contributor.googleauthorEun Seok Kang-
dc.contributor.googleauthorHyun Chul Lee-
dc.contributor.googleauthorBong Soo Cha-
dc.identifier.doi10.1161/JAHA.113.000650-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03301-
dc.contributor.localIdA02810-
dc.contributor.localIdA02989-
dc.contributor.localIdA03996-
dc.contributor.localIdA00068-
dc.contributor.localIdA00903-
dc.contributor.localIdA02796-
dc.contributor.localIdA02759-
dc.relation.journalcodeJ01774-
dc.identifier.eissn2047-9980-
dc.identifier.pmid24572249-
dc.subject.keywordcholesterol-
dc.subject.keywordepidemiology-
dc.subject.keywordhypercholesterolemia-
dc.subject.keywordlow‐density lipoprotein cholesterol-
dc.contributor.alternativeNameLee, Sang Guk-
dc.contributor.alternativeNameLee, Yong Ho-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameCha, Bong Soo-
dc.contributor.alternativeNameKang, Eun Seok-
dc.contributor.alternativeNameKim, Jeong Ho-
dc.contributor.alternativeNameLee, Myung Ha-
dc.contributor.alternativeNameLee, Byung Wan-
dc.contributor.affiliatedAuthorLee, Hyun Chul-
dc.contributor.affiliatedAuthorLee, Sang Guk-
dc.contributor.affiliatedAuthorLee, Yong Ho-
dc.contributor.affiliatedAuthorCha, Bong Soo-
dc.contributor.affiliatedAuthorKang, Eun Seok-
dc.contributor.affiliatedAuthorKim, Jeong Ho-
dc.contributor.affiliatedAuthorLee, Byung Wan-
dc.contributor.affiliatedAuthorLee, Myung Ha-
dc.citation.volume3-
dc.citation.number1-
dc.citation.startPage446-
dc.identifier.bibliographicCitationJOURNAL OF THE AMERICAN HEART ASSOCIATION, Vol.3(1) : 446, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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