Cited 38 times in
Serum Cholesterol Concentration and Prevalence, Awareness, Treatment, and Control of High Low‐Density Lipoprotein Cholesterol in the Korea National Health and Nutrition Examination Surveys 2008–2010: Beyond the Tip of the Iceberg
DC Field | Value | Language |
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dc.contributor.author | 이상국 | - |
dc.contributor.author | 이용호 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | 강은석 | - |
dc.contributor.author | 김정호 | - |
dc.contributor.author | 이명하 | - |
dc.contributor.author | 이병완 | - |
dc.date.accessioned | 2015-01-06T16:29:32Z | - |
dc.date.available | 2015-01-06T16:29:32Z | - |
dc.date.issued | 2014 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98206 | - |
dc.description.abstract | BACKGROUND: The mortality rate from cardiovascular disease (CVD) among young adults has declined less than that in the older population, raising concerns about the increasing prevalence of obesity-related conditions including hypercholesterolemia in the younger population. We investigated the age-standardized mean levels of serum cholesterols and the prevalence, awareness, treatment and control rates of hyper-low-density lipoprotein (LDL)-cholesterolemia based on age. METHODS AND RESULTS: Nationally representative samples of 19 489 subjects aged ≥20 years were analyzed from the Korea National Health and Nutrition Examination Surveys 2008-2010. Hyper-LDL-cholesterolemia was individually evaluated by the 2004 National Cholesterol Education Program Adult Treatment Panel III guidelines. Age-standardized mean levels of total cholesterol, high-density lipoprotein-cholesterol, LDL-cholesterol, and triglycerides were 186.8, 48.0, 112.9, and 136.0 mg/dL, respectively. Age-standardized prevalence of hyper-LDL-cholesterolemia was 23.2% (men, 25.5%; women, 21.8%). Among subjects with hyper-LDL-cholesterolemia, awareness and treatment rates were significantly lower in younger adults (<50 years) compared to older adults ≥50 years (awareness, 8.0% versus 21.5%; treatment, 5.1% versus 18.5%, all Ps<0.001), indicating significant discrepancies in awareness and treatment rates of hypercholesterolemia between younger and older adults. Among subjects aware of their hyper-LDL-cholesterolemia, younger adults were more likely to have controlled LDL-cholesterol than the elderly (82.1% versus 67.5%, P<0.001). CONCLUSIONS: Compared to the elderly, significant proportions of young and middle-aged adults are unaware of their hypercholesterolemia and are not treated with proper lipid-lowering medications. Early screening, education, and proper management should be stressed in national public healthcare policies to reduce the increasing burden of CVD in the younger population with undiagnosed hypercholesterolemia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN HEART ASSOCIATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Distribution | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anticholesteremic Agents/therapeutic use* | - |
dc.subject.MESH | Awareness* | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Cholesterol, LDL/blood* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Health Behavior | - |
dc.subject.MESH | Health Knowledge, Attitudes, Practice* | - |
dc.subject.MESH | Health Surveys | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypercholesterolemia*/blood | - |
dc.subject.MESH | Hypercholesterolemia*/diagnosis | - |
dc.subject.MESH | Hypercholesterolemia*/drug therapy | - |
dc.subject.MESH | Hypercholesterolemia*/epidemiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nutrition Surveys | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Triglycerides/blood | - |
dc.subject.MESH | Young Adult | - |
dc.title | Serum Cholesterol Concentration and Prevalence, Awareness, Treatment, and Control of High Low‐Density Lipoprotein Cholesterol in the Korea National Health and Nutrition Examination Surveys 2008–2010: Beyond the Tip of the Iceberg | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Yong‐ho Lee | - |
dc.contributor.googleauthor | Sang‐Guk Lee | - |
dc.contributor.googleauthor | Myung Ha Lee | - |
dc.contributor.googleauthor | Jeong‐Ho Kim | - |
dc.contributor.googleauthor | Byung‐Wan Lee | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.identifier.doi | 10.1161/JAHA.113.000650 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A02810 | - |
dc.contributor.localId | A02989 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A00903 | - |
dc.contributor.localId | A02796 | - |
dc.contributor.localId | A02759 | - |
dc.relation.journalcode | J01774 | - |
dc.identifier.eissn | 2047-9980 | - |
dc.identifier.pmid | 24572249 | - |
dc.subject.keyword | cholesterol | - |
dc.subject.keyword | epidemiology | - |
dc.subject.keyword | hypercholesterolemia | - |
dc.subject.keyword | low‐density lipoprotein cholesterol | - |
dc.contributor.alternativeName | Lee, Sang Guk | - |
dc.contributor.alternativeName | Lee, Yong Ho | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Kim, Jeong Ho | - |
dc.contributor.alternativeName | Lee, Myung Ha | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Lee, Sang Guk | - |
dc.contributor.affiliatedAuthor | Lee, Yong Ho | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Kim, Jeong Ho | - |
dc.contributor.affiliatedAuthor | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Myung Ha | - |
dc.citation.volume | 3 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 446 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN HEART ASSOCIATION, Vol.3(1) : 446, 2014 | - |
dc.identifier.rimsid | 50716 | - |
dc.type.rims | ART | - |
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