Cited 31 times in
Comparison of the Haas and the Oxford classifications for prediction of renal outcome in patients with IgA nephropathy.
DC Field | Value | Language |
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dc.contributor.author | 이미정 | - |
dc.contributor.author | 임범진 | - |
dc.contributor.author | 정현주 | - |
dc.contributor.author | 최규헌 | - |
dc.contributor.author | 강신욱 | - |
dc.contributor.author | 한승혁 | - |
dc.contributor.author | 구향모 | - |
dc.contributor.author | 권영은 | - |
dc.contributor.author | 김영리 | - |
dc.contributor.author | 김찬호 | - |
dc.contributor.author | 남기헌 | - |
dc.contributor.author | 도화미 | - |
dc.contributor.author | 박경숙 | - |
dc.contributor.author | 안성영 | - |
dc.contributor.author | 오형중 | - |
dc.contributor.author | 유태현 | - |
dc.date.accessioned | 2015-01-06T16:24:58Z | - |
dc.date.available | 2015-01-06T16:24:58Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0046-8177 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98063 | - |
dc.description.abstract | Pathologic features can provide valuable information for determining prognosis in IgA nephropathy (IgAN). However, it is uncertain whether the Oxford classification, a new classification of IgAN, can predict renal outcome better than previous ones. We conducted a retrospective cohort study in 500 patients with biopsy-proven IgAN between January 2002 and December 2010 to compare the ability of the Haas and the Oxford classifications to predict renal outcome. Primary outcome was a doubling of the baseline serum creatinine concentration (D-SCr). During a mean follow-up of 68 months, 52 (10.4%) and 35 (7.0%) developed D-SCr and end-stage renal disease, respectively. There were graded increases in the development of D-SCr in the higher Haas classes. In addition, the primary endpoint of D-SCr occurred more in patients with the Oxford M and T lesions than those without such lesions. In multivariate Cox regression analyses, the Haas class V (HR, 12.19; P=.002) and the Oxford T1 (hazard ratio [HR], 6.68; P<.001) and T2 (HR, 12.16; P<.001) lesions were independently associated with an increased risk of reaching D-SCr. Harrell's C index of each multivariate model with the Haas and the Oxford classification was 0.867 (P=.015) and 0.881 (P=.004), respectively. This was significantly higher than that of model with clinical factors only (C=0.819). However, there was no difference in C-statistics between the 2 models with the Haas and the Oxford classifications (P=.348). This study suggests that the Haas and the Oxford classifications are comparable in predicting progression of IgAN. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | HUMAN PATHOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Creatinine/blood | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glomerulonephritis, IGA/classification* | - |
dc.subject.MESH | Glomerulonephritis, IGA/complications* | - |
dc.subject.MESH | Glomerulonephritis, IGA/pathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Failure, Chronic/etiology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Comparison of the Haas and the Oxford classifications for prediction of renal outcome in patients with IgA nephropathy. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Kyoung Sook Park | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.contributor.googleauthor | Jeong Hae Kie | - |
dc.contributor.googleauthor | Ki Heon Nam | - |
dc.contributor.googleauthor | Mi Jung Lee | - |
dc.contributor.googleauthor | Beom Jin Lim | - |
dc.contributor.googleauthor | Young Eun Kwon | - |
dc.contributor.googleauthor | Yung Ly Kim | - |
dc.contributor.googleauthor | Seong Yeong An | - |
dc.contributor.googleauthor | Chan Ho Kim | - |
dc.contributor.googleauthor | Fa Mee Doh | - |
dc.contributor.googleauthor | Hyang Mo Koo | - |
dc.contributor.googleauthor | Hyung Jung Oh | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Kyu Hun Choi | - |
dc.contributor.googleauthor | Hyeon Joo Jeong | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.identifier.doi | 10.1016/j.humpath.2013.08.019 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03363 | - |
dc.contributor.localId | A03771 | - |
dc.contributor.localId | A04043 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A04304 | - |
dc.contributor.localId | A00203 | - |
dc.contributor.localId | A00232 | - |
dc.contributor.localId | A00277 | - |
dc.contributor.localId | A00703 | - |
dc.contributor.localId | A01037 | - |
dc.contributor.localId | A01244 | - |
dc.contributor.localId | A01315 | - |
dc.contributor.localId | A01423 | - |
dc.contributor.localId | A02236 | - |
dc.contributor.localId | A02417 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A02773 | - |
dc.relation.journalcode | J01011 | - |
dc.identifier.eissn | 1532-8392 | - |
dc.identifier.pmid | 24439222 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0046817713003766 | - |
dc.subject.keyword | IgA nephropathy | - |
dc.subject.keyword | Long-term outcome | - |
dc.subject.keyword | Proteinuria | - |
dc.contributor.alternativeName | Lee, Mi Jung | - |
dc.contributor.alternativeName | Lim, Beom Jin | - |
dc.contributor.alternativeName | Jeong, Hyeon Joo | - |
dc.contributor.alternativeName | Choi, Kyu Hun | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.alternativeName | Han, Seung Hyeok | - |
dc.contributor.alternativeName | Koo, Hyang Mo | - |
dc.contributor.alternativeName | Kwon, Young Eun | - |
dc.contributor.alternativeName | Kie, Jeong Hae | - |
dc.contributor.alternativeName | Kim, Yung Ly | - |
dc.contributor.alternativeName | Kim, Chan Ho | - |
dc.contributor.alternativeName | Nam, Ki Heon | - |
dc.contributor.alternativeName | Doh, Fa Mee | - |
dc.contributor.alternativeName | Park, Kyoung Sook | - |
dc.contributor.alternativeName | An, Seong Yeong | - |
dc.contributor.alternativeName | Oh, Hyung Jung | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Lim, Beom Jin | - |
dc.contributor.affiliatedAuthor | Jeong, Hyeon Joo | - |
dc.contributor.affiliatedAuthor | Choi, Kyu Hun | - |
dc.contributor.affiliatedAuthor | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Han, Seung Hyeok | - |
dc.contributor.affiliatedAuthor | Koo, Hyang Mo | - |
dc.contributor.affiliatedAuthor | Kwon, Young Eun | - |
dc.contributor.affiliatedAuthor | Kie, Jeong Hae | - |
dc.contributor.affiliatedAuthor | Kim, Yung Ly | - |
dc.contributor.affiliatedAuthor | Kim, Chan Ho | - |
dc.contributor.affiliatedAuthor | Nam, Ki Heon | - |
dc.contributor.affiliatedAuthor | Doh, Fa Mee | - |
dc.contributor.affiliatedAuthor | Park, Kyoung Sook | - |
dc.contributor.affiliatedAuthor | An, Seong Yeong | - |
dc.contributor.affiliatedAuthor | Oh, Hyung Jung | - |
dc.contributor.affiliatedAuthor | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Mi Jung | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 45 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 236 | - |
dc.citation.endPage | 243 | - |
dc.identifier.bibliographicCitation | HUMAN PATHOLOGY, Vol.45(2) : 236-243, 2014 | - |
dc.identifier.rimsid | 54363 | - |
dc.type.rims | ART | - |
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