514 790

Cited 13 times in

Nutritional Outcomes in Children with Epidermolysis Bullosa: The Experiences of Two Centers in Korea

DC Field Value Language
dc.contributor.author김수찬-
dc.contributor.author남궁란-
dc.contributor.author박국인-
dc.contributor.author박민수-
dc.contributor.author은호선-
dc.contributor.author이순민-
dc.contributor.author이철-
dc.date.accessioned2015-01-06T16:22:18Z-
dc.date.available2015-01-06T16:22:18Z-
dc.date.issued2014-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/97983-
dc.description.abstractPURPOSE: Epidermolysis bullosa (EB) is associated with variable risks of extracutaneous manifestations and death. Currently, there is limited information on the clinical course and prognosis of EB in Korea. This study analyzed the nutritional outcomes, clinical morbidity, and mortality of children with EB. MATERIALS AND METHODS: Thirty patients, admitted to Severance Hospital and Gangnam Severance Hospital, from January 2001 to December 2011, were retrospectively enrolled. All patients were diagnosed with EB classified by dermatologists. RESULTS: Among the 30 patients, 5 patients were diagnosed with EB simplex, four with junctional EB, and 21 with dystrophic EB. Wound infection occurred in 47% of the patients, and blood culture-proven sepsis was noted in 10% of the patients. Two (9.2%) patients had esophageal stricture and 11 (52.4%) of the dystrophic EB patients received reconstructive surgery due to distal extremity contracture. There were five mortalities caused by sepsis, failure to thrive, and severe metabolic acidosis with dehydration. According to nutrition and growth status, most of the infants (97%) were born as appropriate for gestational age. However, at last follow-up, 56% of the children were below the 3rd percentile in weight, and 50% were below the 3rd percentile in weight for height. Sixty percent of the children had a thrive index below -3. CONCLUSION: Postnatal growth failure is a serious problem in children with EB. Strategies to maximize nutritional support could alleviate growth failure in children with EB, and thus improve clinical outcomes.-
dc.description.statementOfResponsibilityopen-
dc.format.extent264~269-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBirth Weight/physiology-
dc.subject.MESHEpidermolysis Bullosa/physiopathology*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfant, Newborn-
dc.subject.MESHKorea-
dc.subject.MESHMale-
dc.subject.MESHPregnancy-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.titleNutritional Outcomes in Children with Epidermolysis Bullosa: The Experiences of Two Centers in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorKyu-Yeun Kim-
dc.contributor.googleauthorRan Namgung-
dc.contributor.googleauthorSoon Min Lee-
dc.contributor.googleauthorSoo Chan Kim-
dc.contributor.googleauthorHo Sun Eun-
dc.contributor.googleauthorMin Soo Park-
dc.contributor.googleauthorKook In Park-
dc.contributor.googleauthorChul Lee-
dc.identifier.doi10.3349/ymj.2014.55.1.264-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01241-
dc.contributor.localIdA01438-
dc.contributor.localIdA01468-
dc.contributor.localIdA02635-
dc.contributor.localIdA02905-
dc.contributor.localIdA03253-
dc.contributor.localIdA00637-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid24339316-
dc.subject.keywordEpidermolysis bullosa-
dc.subject.keywordgrowth failure-
dc.subject.keywordnutritional outcome-
dc.contributor.alternativeNameKim, Soo Chan-
dc.contributor.alternativeNameNamgung, Ran-
dc.contributor.alternativeNamePark, Kook In-
dc.contributor.alternativeNamePark, Min Soo-
dc.contributor.alternativeNameEun, Ho Seon-
dc.contributor.alternativeNameLee, Soon Min-
dc.contributor.alternativeNameLee, Chul-
dc.contributor.affiliatedAuthorNamgung, Ran-
dc.contributor.affiliatedAuthorPark, Kook In-
dc.contributor.affiliatedAuthorPark, Min Soo-
dc.contributor.affiliatedAuthorEun, Ho Seon-
dc.contributor.affiliatedAuthorLee, Soon Min-
dc.contributor.affiliatedAuthorLee, Chul-
dc.contributor.affiliatedAuthorKim, Soo Chan-
dc.citation.volume55-
dc.citation.number1-
dc.citation.startPage264-
dc.citation.endPage269-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.55(1) : 264-269, 2014-
dc.identifier.rimsid53468-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.