8 1115

Cited 19 times in

Risk factors for 28-day mortality in elderly patients with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae bacteremia

DC Field Value Language
dc.contributor.author송제은-
dc.contributor.author안진영-
dc.contributor.author오동현-
dc.contributor.author정수진-
dc.contributor.author최준용-
dc.contributor.author한상훈-
dc.contributor.author구남수-
dc.contributor.author김민형-
dc.contributor.author김선빈-
dc.contributor.author김용찬-
dc.contributor.author김준명-
dc.contributor.author김창오-
dc.contributor.author김혜원-
dc.contributor.author송영구-
dc.date.accessioned2015-01-06T16:20:28Z-
dc.date.available2015-01-06T16:20:28Z-
dc.date.issued2014-
dc.identifier.issn0167-4943-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/97928-
dc.description.abstractGram-negative bacteremia is common in elderly patients and, compared with younger patients, mortality rates in bacteremic elderly patients are high. ESBL-producing organisms were one of the most important risk factors associated with mortality. In addition, older age is one of risk factors for colonization or infection with ESBL-producing organisms. We conducted a retrospective cohort study to evaluate risk factors of all-cause 28-day mortality in elderly patients with ESBL-producing Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) bacteremia. Patients aged 65 years or older, who had one or more blood cultures positive for E. coli and K. pneumoniae and who were hospitalized between January 2006 and December 2010 at a tertiary-care teaching hospital, were included. 191 bacteremic elderly patients were eligible for the study. The all-cause 28-day mortality rate was 24.6% (47/191). In multivariate analysis, prior antimicrobial therapy (p = 0.014) and an elevated SOFA score (p < 0.001) were independent risk factors for increased mortality, while urinary tract infection (UTI) was an independent determinant for non-mortality (p = 0.011). In the current study, prior antimicrobial therapy within 30 days, an elevated SOFA score and nonurinary source of infection were significantly associated with adverse outcomes in elderly patients with ESBL-producing gram-negative bacteremia.-
dc.description.statementOfResponsibilityopen-
dc.format.extent105~109-
dc.relation.isPartOfARCHIVES OF GERONTOLOGY AND GERIATRICS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHBacteremia/microbiology-
dc.subject.MESHBacteremia/mortality*-
dc.subject.MESHEscherichia coli/enzymology*-
dc.subject.MESHEscherichia coli/isolation & purification-
dc.subject.MESHEscherichia coli Infections/microbiology-
dc.subject.MESHEscherichia coli Infections/mortality*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGeriatric Assessment/methods*-
dc.subject.MESHHumans-
dc.subject.MESHKlebsiella Infections/microbiology-
dc.subject.MESHKlebsiella Infections/mortality*-
dc.subject.MESHKlebsiella pneumoniae/enzymology*-
dc.subject.MESHKlebsiella pneumoniae/isolation & purification-
dc.subject.MESHMale-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurvival Rate/trends-
dc.subject.MESHTime Factors-
dc.subject.MESHbeta-Lactamases/secretion*-
dc.titleRisk factors for 28-day mortality in elderly patients with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae bacteremia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorYong Chan Kim-
dc.contributor.googleauthorMin Hyung Kim-
dc.contributor.googleauthorJe Eun Song-
dc.contributor.googleauthorDong Hyun Oh-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorSun Bean Kim-
dc.contributor.googleauthorHye-won Kim-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorChang Oh Kim-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorJune Myung Kim-
dc.contributor.googleauthorJun Yong Choi-
dc.identifier.doi10.1016/j.archger.2013.07.002-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02059-
dc.contributor.localIdA02267-
dc.contributor.localIdA02361-
dc.contributor.localIdA03638-
dc.contributor.localIdA04191-
dc.contributor.localIdA04286-
dc.contributor.localIdA00189-
dc.contributor.localIdA00480-
dc.contributor.localIdA00547-
dc.contributor.localIdA00752-
dc.contributor.localIdA00953-
dc.contributor.localIdA01044-
dc.contributor.localIdA01176-
dc.contributor.localIdA02037-
dc.relation.journalcodeJ00219-
dc.identifier.eissn1872-6976-
dc.identifier.pmid23988261-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S016749431300109X-
dc.subject.keywordESBL-
dc.subject.keywordElderly patients-
dc.subject.keywordGram-negative bacteremia-
dc.subject.keywordMortality-
dc.subject.keywordRisk factor-
dc.contributor.alternativeNameSong, Je Eun-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameOh, Dong Hyun-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameKim, Min Hyung-
dc.contributor.alternativeNameKim, Sun Bean-
dc.contributor.alternativeNameKim, Yong Chan-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameKim, Hye Won-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.affiliatedAuthorSong, Je Eun-
dc.contributor.affiliatedAuthorAhn, Jin Young-
dc.contributor.affiliatedAuthorOh, Dong Hyun-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.contributor.affiliatedAuthorKu, Nam Su-
dc.contributor.affiliatedAuthorKim, Min Hyung-
dc.contributor.affiliatedAuthorKim, Sun Bean-
dc.contributor.affiliatedAuthorKim, Yong Chan-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorKim, Chang Oh-
dc.contributor.affiliatedAuthorKim, Hye Won-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.rights.accessRightsfree-
dc.citation.volume58-
dc.citation.number1-
dc.citation.startPage105-
dc.citation.endPage109-
dc.identifier.bibliographicCitationARCHIVES OF GERONTOLOGY AND GERIATRICS, Vol.58(1) : 105-109, 2014-
dc.identifier.rimsid53436-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.