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신장이식을 위한 신적출 후 기증자 신기능의 장기적인 변화

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dc.contributor.author김명수-
dc.contributor.author김순일-
dc.contributor.author김유선-
dc.contributor.author안형준-
dc.contributor.author장혜경-
dc.contributor.author주만기-
dc.date.accessioned2014-12-21T17:31:24Z-
dc.date.available2014-12-21T17:31:24Z-
dc.date.issued2007-
dc.identifier.issn1298-1711-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/97751-
dc.description.abstractPurpose: Occurrence of renal failure and its related complications such as hypertension are long-term problems after donor nephrectomy for living donor kidney transplantation. We retrospectively reviewed renal function of unilateral kidney donor. Methods: From 669 living donors for kidney transplantation from December 1998 to October 2006, laboratory data related to renal function are collected from hospital medical record retrospectively in 251 (37.5%) donors who were followed-up after discharge. The selection criteria of donors were: 1) pre-nephrectomy serum creatinine level below 1.5 mg/dL, 2) no radiologic abnormality in bilateral kidney. The donor nephrectomy was performed by conventional open nephrectomy or video assisted minilaparotomy surgery. The estimated glomerular filtration rate (e-GFR) by Modification of Diet in Renal Disease (MDRD) study was used as renal function monitoring parameter. Results: In immediate post-nephrectomy period, e-GFR was decreased to 67.8±14.6% of pre-nephrectomy level (93.8±19.9 mL/min/1.73 m2). The urinary protein excretion for 24 hours was increased to 255% of pre-nephrectomy level (76.4±44.6 mg/day), but cases with proteinuria more than 300 mg per day were only 4 cases (1.7%, 4/251). After 14.0±15.2 months follow-up (range: 1~80 months), two cases (0.8%, 2/251) of renal failure (chronic kidney disease stage 5) were found. Relative renal function (post-nephrectomy e-GFR ratio versus pre-nephrectomy e-GFR, %) was increased by post-nephrectomy duration. The mean scores of e-GFR ratio within post-nephrectomy 2 months, 3~11 months, 12~23 months and after 24 months were 64.8±10.4%, 66.4±9.7%, 69.5±10.9% and 75.8±17.6% respectively. The relative e-GFR ratio after 24 months was significantly different from those of within 24 months (P<0.0001 by ANOVA). In linear regression analysis, mean increment of e-GFR ratio per post-nephrectomy year was 2.88%. Conclusion: In spite of possibility of renal failure, our study shows the long-term compensation of residual renal function after nephrectomy.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageJournal of the Korean Society for Transplantation-
dc.publisherJournal of the Korean Society for Transplantation-
dc.relation.isPartOfJournal of the Korean Society for Transplantation-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title신장이식을 위한 신적출 후 기증자 신기능의 장기적인 변화-
dc.title.alternativeLong-term Change of Renal Function after Donor Nephrectomy for Kidney Transplantation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthor장혜경-
dc.contributor.googleauthor주만기-
dc.contributor.googleauthor김유선-
dc.contributor.googleauthor김순일-
dc.contributor.googleauthor김명수-
dc.contributor.googleauthor전경옥-
dc.contributor.googleauthor김현정-
dc.contributor.googleauthor안형준-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00649-
dc.contributor.localIdA00785-
dc.contributor.localIdA02273-
dc.contributor.localIdA03494-
dc.contributor.localIdA03949-
dc.contributor.localIdA00424-
dc.relation.journalcodeJ01858-
dc.identifier.eissn2508-2604-
dc.contributor.alternativeNameKim, Myoung Soo-
dc.contributor.alternativeNameKim, Soon Il-
dc.contributor.alternativeNameKim, Yu Seun-
dc.contributor.alternativeNameAhn, Hyoung Joon-
dc.contributor.alternativeNameChang, Hye Kyung-
dc.contributor.alternativeNameJoo, Man Ki-
dc.contributor.affiliatedAuthorKim, Soon Il-
dc.contributor.affiliatedAuthorKim, Yu Seun-
dc.contributor.affiliatedAuthorAhn, Hyoung Joon-
dc.contributor.affiliatedAuthorChang, Hye Kyung-
dc.contributor.affiliatedAuthorJoo, Man Ki-
dc.contributor.affiliatedAuthorKim, Myoung Soo-
dc.rights.accessRightsnot free-
dc.citation.volume21-
dc.citation.number1-
dc.citation.startPage75-
dc.citation.endPage80-
dc.identifier.bibliographicCitationJournal of the Korean Society for Transplantation, Vol.21(1) : 75-80, 2007-
dc.identifier.rimsid47682-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers

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