Cited 8 times in
Different Modulation of the Cortical Silent Period by Two Phases of Short Interval Intracortical Inhibition
DC Field | Value | Language |
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dc.contributor.author | 손영호 | - |
dc.date.accessioned | 2014-12-21T17:24:52Z | - |
dc.date.available | 2014-12-21T17:24:52Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/97545 | - |
dc.description.abstract | PURPOSE: To investigate the influence of 2 phases of short interval intracortical inhibition (SICI) on the cortical silent period (SP). MATERIALS AND METHODS: Single- and paired-pulse transcranial magnetic stimulations (TMSs) at 1 and 2.5ms interstimulus intervals (ISIs) were applied to the left motor cortex in 12 healthy subjects while their right hand muscles were moderately activated. Conditioning stimulation intensity was 90% of the active motor threshold (AMT). Test stimulation intensities were 120, 140, 160, 180, 200, 220, 240, 260% of the AMT and at 100% of the maximal stimulator output, the order of which was arranged randomly. The rectified electromyography area of motor evoked potential (MEP) and duration of the SP were measured off-line using a computerized program. RESULTS: At high-test stimulation intensities, MEP areas were saturated in both single- and paired-pulse stimulations, except that saturated MEPs were smaller for the paired-pulse TMS at 1ms ISI than for the other conditions. As the test stimulation intensity increased, SP was progressively prolonged in both single- and paired-pulse stimulations but was shorter in paired-pulse than single-pulse TMS. Overall, the ratio of SP duration/MEP area was comparable between single- and paired-pulse TMS except for the paired-pulse TMS at 1 ms ISI with a test stimulation intensity at 140-180% of the AMT, in which the ratio was significantly higher than in the single pulse TMS. CONCLUSION: These results suggest that 2 phases of SICI modulate MEP saturation and SP duration differently and provide additional evidence supporting the view that 2 phases of SICI are mediated by different inhibitory mechanisms. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 795~801 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Different Modulation of the Cortical Silent Period by Two Phases of Short Interval Intracortical Inhibition | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | Suk Yun Kang | - |
dc.contributor.googleauthor | Hae-Won Shin | - |
dc.contributor.googleauthor | Young Ho Sohn | - |
dc.identifier.doi | 10.3349/ymj.2007.48.5.795 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01982 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.contributor.alternativeName | Sohn, Young Ho | - |
dc.contributor.affiliatedAuthor | Sohn, Young Ho | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 48 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 795 | - |
dc.citation.endPage | 801 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.48(5) : 795-801, 2007 | - |
dc.identifier.rimsid | 57439 | - |
dc.type.rims | ART | - |
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