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Comparison of postpolypectomy bleeding between epinephrine and saline submucosal injection for large colon polyps by conventional polypectomy: A prospective randomized, multicenter study
DC Field | Value | Language |
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dc.contributor.author | 김원호 | - |
dc.date.accessioned | 2014-12-21T17:21:50Z | - |
dc.date.available | 2014-12-21T17:21:50Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/97447 | - |
dc.description.abstract | AIM: To evaluate and compare the clinical outcomes of prophylactic submucosal saline-epinephrine injection and saline injection alone for large colon polyps by conventional polypectomy. METHODS: A prospective study was conducted from July 2003 to July 2004 at 11 tertiary endoscopic centers. Large colon polyps (> 10 mm in diameter) were randomized to undergo endoscopic polypectomy with submucosal saline-epinephrine injection (epinephrine group) or normal saline injection (saline group). Endoscopic polypectomy was performed by the conventional snare method, and early (< 12 h) and late bleeding complications (12 h-30 d) were observed. RESULTS: A total of 561 polyps in 486 patients were resected by endoscopic polypectomy. Overall, bleeding complications occurred in 7.6% (37/486) of the patients, including 4.9% (12/244) in the epinephrine group, and 10.3% (25/242) in the saline group. Early and late postpolypectomy bleeding (PPB) occurred in 6.6% (32/486) and 1% (5/486) of the patients, respectively, including 4.5% (11/244), 0.4% (1/244) in the epinephrine group, and 8.7% (21/242), 1.7% (4/242) in the saline group. No significant differences in the rates of overall, early and late PPB were observed between the 2 groups. Multivariate stepwise logistic regression analysis revealed that large size (> 2 cm) and neoplastic polyps were independently and significantly associated with the presence of PPB. CONCLUSION: The prophylactic submucosal injection of diluted epinephrine does not appear to provide an additional advantage over the saline injection alone for the prevention of PPB. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 2973~2977 | - |
dc.relation.isPartOf | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Comparison of postpolypectomy bleeding between epinephrine and saline submucosal injection for large colon polyps by conventional polypectomy: A prospective randomized, multicenter study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Suck-Ho Lee | - |
dc.contributor.googleauthor | Il-Kwun Chung | - |
dc.contributor.googleauthor | Jae Suk Song | - |
dc.contributor.googleauthor | Dong-Soo Han | - |
dc.contributor.googleauthor | Hwang Choi | - |
dc.contributor.googleauthor | Jai-Hyun Choi | - |
dc.contributor.googleauthor | Yoon-Tae Jeen | - |
dc.contributor.googleauthor | Sung-Ae Jung | - |
dc.contributor.googleauthor | Byeong Ik Jang | - |
dc.contributor.googleauthor | Suk-Kyun Yang | - |
dc.contributor.googleauthor | Jeong-Sik Byeon | - |
dc.contributor.googleauthor | Hyo-Jong Kim | - |
dc.contributor.googleauthor | Dong-IL Park | - |
dc.contributor.googleauthor | Hyun-Soo Kim | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.contributor.googleauthor | Bong-Min Ko | - |
dc.contributor.googleauthor | Jin-Oh Kim | - |
dc.contributor.googleauthor | Sun-Joo Kim | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00774 | - |
dc.relation.journalcode | J02795 | - |
dc.identifier.eissn | 2219-2840 | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | Kim, Won Ho | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 13 | - |
dc.citation.number | 21 | - |
dc.citation.startPage | 2973 | - |
dc.citation.endPage | 2977 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF GASTROENTEROLOGY, Vol.13(21) : 2973-2977, 2007 | - |
dc.identifier.rimsid | 55886 | - |
dc.type.rims | ART | - |
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